Aligning sequencing reads onto a reference is an essential step of the majority of genomic
analysis pipelines. Computational algorithms for read alignment have evolved in …

Current hardware approaches to biomimetic or neuromorphic artificial intelligence rely on
elaborate transistor circuits to simulate biological functions. However, these can instead be …

Viral hepatitis B and C virus (HBV and HCV) are responsible for the most of chronic liver
disease worldwide and are transmitted by parenteral route, sexual and vertical transmission …

Motivation High-throughput sequencing technologies are used increasingly not only in viral
genomics research but also in clinical surveillance and diagnostics. These technologies …

Rapidly evolving RNA viruses prevail within a host as a collection of closely related variants,
referred to as viral quasispecies. Advances in high-throughput sequencing (HTS) …

A viral quasispecies, the ensemble of viral strains populating an infected person, can be
highly diverse. For optimal assessment of virulence, pathogenesis, and therapy selection …

The unprecedented coverage offered by next-generation sequencing (NGS) technology has
facilitated the assessment of the population complexity of intra-host RNA viral populations at …

Currently, the standard practice for assembling next-generation sequencing (NGS) reads of
viral genomes is to summarize thousands of individual short reads into a single consensus …

Background Recent advancements in next-generation sequencing have rapidly improved
our ability to study genomic material at an unprecedented scale. Despite substantial …

Viruses shape a diversity of ecosystems by modulating their microbial, eukaryotic, or plant
host metabolism. The complexity of virus–host interaction networks is progressively …