Aberrant ganglioside functions to underpin dysregulated myelination, insulin signalling, and cytokine expression: is there a link and a room for therapy?

E Svirin, J de Munter, A Umriukhin, E Sheveleva… - Biomolecules, 2022 - mdpi.com
Gangliosides are molecules widely present in the plasma membranes of mammalian cells,
participating in a variety of processes, including protein organization, transmembrane …

Lipid metabolism: Novel approaches for managing idiopathic epilepsy

C Wang, J Zhai, X Zhou, Y Chen - Neuropeptides, 2024 - Elsevier
Epilepsy is a common neurological condition characterized by abnormal neuronal activity,
often leading to cellular damage and death. There is evidence to suggest that lipid …

Complement C4-deficient mice have a high mortality rate during PTZ-induced epileptic seizures, which correlates with cognitive problems and the deficiency in the …

T Veremeyko, R Jiang, M He… - Frontiers in Cellular …, 2023 - frontiersin.org
Complement system plays an important role in the immune defense against pathogens;
however, recent studies demonstrated an important role of complement subunits C1q, C4 …

Neurological insights on two siblings with GM3 synthase deficiency due to novel compound heterozygous ST3GAL5 variants

S Watanabe, M Lei, E Nakagawa, E Takeshita… - Brain and …, 2023 - Elsevier
Abstract Background ST3GAL5 encodes GM3 synthase (ST3 beta-galactoside alpha-2, 3-
sialyltransferase 5; ST3GAL5), which synthesizes GM3 by transferring sialic acid to …

Identify Candidate Genes Associated with the Weight and Egg Quality Traits in Wenshui Green Shell-Laying Chickens by the Copy Number Variation-Based Genome …

S Yang, C Ning, C Yang, W Li, Q Zhang, D Wang… - Veterinary …, 2024 - mdpi.com
Simple Summary The Wenshui green shell-laying chicken is an improved breed crossed
from the Wenshang reed-feather chicken and Xinyang green shell-laying chicken, whose …