Hybrid cardiovascular mock circuits (HMC), designed for dynamic testing of Ventricular
Assist Devices (VAD), offer physiologic accuracy by sequestering model complexity in silico …

Significant advances in biomedical science often leverage powerful computational and
experimental modeling platforms. We present a framework named physiology simulation …

Background Valve dysfunction is a common cardiovascular pathology. Despite significant
clinical research, there is little formal study of how valve dysfunction affects overall …

Long‐term mechanical circulatory assistance opened new problems in ventricular assist
device—patient interaction, especially in relation to autonomic controls. Modeling studies …

The paper presents a hybrid (hydro-numerical) circulatory model built to be used as a
complementary tool for clinical purposes. It was developed at the Institute of Biocybernetics …

Medical device prototype developed for use on human has to be tested in various aspect;
from numerical simulation, laboratory testing, testing on animals and finally human trial …

Despite 50 years of research to assess the intra‐aortic balloon pump (IABP) effects on
patients' hemodynamics, some issues related to the effects of this therapy are still not fully …

Aim of this work was to develop a modular computational model able to interact with
ventricular assist devices (VAD) for research and educational applications. The lumped …

This article presents a new device designed to simulate in vitro flow rates, pressures, and
other parameters representing normal and diseased conditions of the human cardiovascular …

We investigated the effects of the intra‐aortic balloon pump (IABP) on endocardial viability
ratio (EVR), cardiac output (CO), end‐systolic (Ves) and end‐diastolic (Ved) ventricular …