Reactive Oxygen Species-Responsive Pillararene-Embedded Covalent Organic Frameworks with Amplified Antimicrobial Photodynamic Therapy for the Targeted …

S Liang, MH Li, ML Qi, H Hui, HP Zhang, J Zhou… - Nano Letters, 2024 - ACS Publications
Reactive oxygen species (ROS)-responsive drug delivery systems possess immense
potential for targeted delivery and controlled release of therapeutics. However, the rapid …

Concurrent Subcellular Delivery of Hydrogen Sulfide and a Payload with Near-Infrared Light

K Hanc, H Janeková, P Štacko - JACS Au, 2024 - ACS Publications
Hydrogen sulfide (H2S) is a gaseous signaling molecule, exerting crucial regulatory
functions in organelles and cellular environments. H2S exhibits high therapeutic potential …

[HTML][HTML] An Examination of Chemical Tools for Hydrogen Selenide Donation and Detection

RA Hankins, JC Lukesh - Molecules, 2024 - mdpi.com
Hydrogen selenide (H2Se) is an emerging biomolecule of interest with similar properties to
that of other gaseous signaling molecules (ie, gasotransmitters that include nitric oxide …

Development of a Bioorthogonal Click-to-Release Reaction for Hydrogen Polysulfide (H2Sn) Detection

X Tong, J Chen, M Wang, J Liu, J Li, X Wang… - Analytical …, 2024 - ACS Publications
In this study, we present an innovative “click-to-release” strategy for the design of highly
specific H2S n bioorthogonal probes that undergo a specific click reaction with H2S n and …

Esterase-Activated Hydrogen Sulfide Donors with Self-Reporting Fluorescence Properties and Highly Tunable Rates of Delivery

C Zhu, C Chen, DE Weaver, JC Lukesh - ACS Chemical Biology, 2024 - ACS Publications
Hydrogen sulfide (H2S) has emerged as a significant biomolecule with diverse activities,
akin to other gaseous signaling molecules such as nitric oxide (NO) and carbon monoxide …

Research Progress in the Field of Hydrogen Sulfide Donors in the Last Five Years

Q Pang, F Huo, C Yin - ChemBioChem, 2024 - Wiley Online Library
Hydrogen sulfide (H2S) serves as the third gasotransmitter, crucial in various physiological
processes involving its production and metabolism. Elevated levels of H2S can result in …

Self-correcting ratiometric fluorescence assay for H2S detection in live cells and releasing agents

NY Kim, MH Lee - Sensors and Actuators B: Chemical, 2025 - Elsevier
Hydrogen sulfide (H 2 S) is both a biologically significant signaling molecule, and a harmful
gas that is generated in the environment; thus, its detection and monitoring are required in …

A Spatiotemporally Controlled and Mitochondria-Targeted Prodrug of Hydrogen Sulfide Enables Mild Mitochondrial Uncoupling for the Prevention of Lipid Deposition

X Zhang, M Ye, Y Ge, C Xiao, K Cui… - Journal of Medicinal …, 2024 - ACS Publications
Mild mitochondrial uncoupling offers therapeutic benefits for various diseases like obesity by
regulating cellular energy metabolism. However, effective chemical intervention tools for …

Integrated Sensing Platform Validated for the Efficient and On-Site Screening of Amine-Containing Illicit Drugs

J Yao, C Yang, R Wen, T Liu, L Ding, Z Yao… - ACS sensors, 2024 - ACS Publications
Efficient and reliable technologies for the on-site detection of illicit drugs are important in
drug-facilitated crime investigations. However, the development of such technologies is …

A Near-Infrared Fluorescent Probe with Large Stokes Shift for Sensitive Detection of Hydrogen Sulfide in Environmental Water, Food Spoilage, and Biological Systems

Y Chen, J Bao, X Pan, Q Chen, J Yan… - The Journal of …, 2024 - ACS Publications
Hydrogen sulfide (H2S) is an important endogenous gas transmitter that plays a critical role
in various physiological and pathological processes and can also cause a negative impact …