The role of hydrogen sulfide in regulation of cell death following neurotrauma and related neurodegenerative and psychiatric diseases

S Rodkin, C Nwosu, A Sannikov, M Raevskaya… - International Journal of …, 2023 - mdpi.com
Injuries of the central (CNS) and peripheral nervous system (PNS) are a serious problem of
the modern healthcare system. The situation is complicated by the lack of clinically effective …

Reactive sulfur species and their significance in health and disease

M Iciek, A Bilska-Wilkosz, M Kozdrowicki… - Bioscience …, 2022 - portlandpress.com
Reactive sulfur species (RSS) have been recognized in the last two decades as very
important molecules in redox regulation. They are involved in metabolic processes and, in …

Role of 3-Mercaptopyruvate sulfurtransferase (3-MST) in physiology and disease

SP Rao, P Dobariya, H Bellamkonda, SS More - Antioxidants, 2023 - mdpi.com
3-mercaptopyruvate sulfurtransferase (3-MST) plays the important role of producing
hydrogen sulfide. Conserved from bacteria to Mammalia, this enzyme is localized in …

Cellular turnover and degradation of the most common missense cystathionine beta‐synthase variants causing homocystinuria

E Mijatovic, K Ascenção, C Szabo, T Majtan - Protein Science, 2024 - Wiley Online Library
Homocystinuria (HCU) due to cystathionine beta‐synthase (CBS) deficiency is the most
common inborn error of sulfur amino acid metabolism. Recent work suggests that missense …

[HTML][HTML] Role of hydrogen sulfide in the regulation of lipid metabolism: Implications on cardiovascular health

F Lorenzo, P Eugenia, C Vincenzo, T Lara - Life sciences, 2024 - Elsevier
Abstract The World Health Organization (WHO) defines obesity as an urgency for health and
a social emergency. Today around 39% of people is overweight, of these over 13% is …

Role of cystathionine β-synthase and 3-mercaptopyruvate sulfurtransferase in the regulation of proliferation, migration, and bioenergetics of murine breast cancer cells

SS Santos, LOCP Rodrigues, V Martins, M Petrosino… - Antioxidants, 2023 - mdpi.com
Cystathionine β-synthase (CBS), CSE (cystathionine γ-lyase) and 3-mercaptopyruvate
sulfurtransferase (3-MST) have emerged as three significant sources of hydrogen sulfide …

Clinical potential of hydrogen sulfide in peripheral arterial disease

C Bechelli, D Macabrey, S Deglise… - International Journal of …, 2023 - mdpi.com
Peripheral artery disease (PAD) affects more than 230 million people worldwide. PAD
patients suffer from reduced quality of life and are at increased risk of vascular complications …

Polysulfides derived from the hydrogen sulfide and persulfide donor P* inhibit IL-1β-mediated inducible nitric oxide synthase signaling in ATDC5 cells: are CCAAT …

M Trummer, E Galardon, B Mayer, G Steiner, T Stamm… - Nitric Oxide, 2022 - Elsevier
Hydrogen sulfide (H 2 S) emerged as an essential signaling molecule exerting beneficial
effects in various cardiovascular, neurodegenerative, or musculoskeletal diseases with an …

Increased hydrogen sulfide turnover serves a cytoprotective role during the development of replicative senescence

A Kieronska-Rudek, K Ascencao, S Chlopicki… - Biochemical …, 2024 - Elsevier
The mammalian gasotransmitter hydrogen sulfide (H 2 S) is produced by enzymes such as
cystathionine β-synthase (CBS), cystathionine γ-lyase (CSE), 3-mercaptopyruvate …

[HTML][HTML] Role of 3-mercaptopyruvate sulfurtransferase in cancer: Molecular mechanisms and therapeutic perspectives

K Zhang, YW Zhu, AQ Tang, ZT Zhou, YL Yang… - Translational …, 2025 - Elsevier
The occurrence and development of tumor is mediated by a wide range of complex
mechanisms. Subsequent to nitric oxide and carbon monoxide, hydrogen sulfide (H 2 S) …