MAIT cells and the microbiome

MF Jabeen, TSC Hinks - Frontiers in Immunology, 2023 - frontiersin.org
Mucosal associated invariant T (MAIT) cells are innate-like T lymphocytes, strikingly
enriched at mucosal surfaces and characterized by a semi-invariant αβ T cell receptor (TCR) …

Classic costimulatory interactions in MAIT cell responses: from gene expression to immune regulation

NI Wang, M Ninkov… - Clinical and Experimental …, 2023 - academic.oup.com
Mucosa-associated invariant T (MAIT) cells are evolutionarily conserved, innate-like T
lymphocytes with enormous immunomodulatory potentials. Due to their strategic …

Identifying and ranking causal microbial biomarkers for colorectal cancer at different cancer subsites and stages: a Mendelian randomization study

H Li, D Sheng, C Jin, G Zhao, L Zhang - Frontiers in oncology, 2023 - frontiersin.org
Introduction The gut microbiome is directly involved in colorectal carcinogenesis, but much
of the epidemiological evidence for the effect of the gut microbiome on colorectal cancer …

Safety and efficacy assessment of fecal microbiota transplantation as an adjunctive treatment for IgA nephropathy: an exploratory clinical trial

W Zhi, A Li, Q Wang, X Yuan, J Qing, C Zhang… - Scientific Reports, 2024 - nature.com
To assess the safety and efficacy of fecal microbiota transplantation (FMT) as an adjunctive
therapeutic intervention for IgA nephropathy (IgAN). Fifteen patients with IgA nephropathy …

Glucose-lowering effects of a synbiotic combination containing Pediococcus acidilactici in C. elegans and mice

D Yavorov-Dayliev, FI Milagro, J Ayo, M Oneca… - Diabetologia, 2023 - Springer
Aims/hypothesis Modulation of gut microbiota has emerged as a promising strategy to treat
or prevent the development of different metabolic diseases, including type 2 diabetes and …

Is weight-adjusted waist index more strongly associated with diabetes than body mass index and waist circumference?: Results from the database large community …

J Wu, J Guo - Plos one, 2024 - journals.plos.org
Background The uncertainty regarding the correlation between the weight-adjusted waist
index (WWI) and diabetes within the National Health and Nutrition Examination Survey …

Intestinal IL-33 promotes microbiota-derived trimethylamine N-oxide synthesis and drives metabolic dysfunction-associated steatotic liver disease progression by …

S Hai, X Li, E Xie, W Wu, Q Gao, B Yu, J Hu, F Xu… - Hepatology, 2024 - journals.lww.com
Hepatology Publish Ahead of Print DOI:10.1097/HEP.0000000000000985 Page 1 Intestinal
IL-33 promotes microbiota-derived trimethylamine N-oxide synthesis and drives metabolic …

Effect of Lacticaseibacillus casei LC2W Supplementation on Glucose Metabolism and Gut Microbiota in Subjects at High Risk of Metabolic Syndrome: A Randomized …

D Wang, X Wang, J Han, C You, Z Liu, Z Wu - Probiotics and Antimicrobial …, 2024 - Springer
Metabolic syndrome (MetS) is a global epidemic complex and will cause serious metabolic
comorbidities without treatment. A prevention strategy for MetS development has been …

Bacteroides and NAFLD: pathophysiology and therapy

J Zhang, J Zhou, Z He, H Li - Frontiers in microbiology, 2024 - frontiersin.org
Non-alcoholic fatty liver disease (NAFLD) is a prevalent chronic liver condition observed
globally, with the potential to progress to non-alcoholic steatohepatitis (NASH), cirrhosis …

The gut microbiome and HLA-B27-associated anterior uveitis: a case-control study

SC Morandi, EL Herzog, M Munk, M Kreuzer… - Journal of …, 2024 - Springer
Background The human gut microbiome (GM) is involved in inflammation and immune
response regulation. Dysbiosis, an imbalance in this ecosystem, facilitates pathogenic …