Microglia are the primary innate immune cells in the CNS. In the healthy brain, they exhibit a
unique molecular homeostatic 'signature', consisting of a specific transcriptional profile and …

Microglia, the immune cells of the central nervous system, have long been a subject of study
in the Alzheimer's disease (AD) field due to their dramatic responses to the pathophysiology …

Microglia, of myeloid origin, play fundamental roles in the control of immune responses and
the maintenance of central nervous system homeostasis. These cells, just like peripheral …

Depending on the species, microglial cells represent 5–20% of glial cells in the adult brain.
As the innate immune effector of the brain, microglia are involved in several functions …

Radiation-induced late brain injury consisting of vascular abnormalities, demyelination,
white matter necrosis, and cognitive impairment has been described in patients subjected to …

The peripheral immune system plays a critical role in aging and in the response to brain
injury. Emerging data suggest inflammatory responses are exacerbated in older animals …

Stroke is one of the most common causes of death worldwide. The subsequent development
of neuroinflammation and brain edema dramatically increases the risks associated with …

Radiation-induced brain injury (RIBI) after radiotherapy has become an increasingly
important factor affecting the prognosis of patients with head and neck tumor. With the …

Responses of the central nervous system (CNS) to stressors and injuries, such as ionising
radiation, are modulated by the concomitant responses of the brains innate immune effector …

Microglia, the innate immune cells of the central nervous system, play a pivotal role in the
modulation of neuroinflammation. Neuroinflammation has been implicated in many diseases …