Neural Circuit Transitions Supporting Developmentally Specific Social Behavior

NC Ferrara, A Che, B Briones… - Journal of …, 2023 - Soc Neuroscience
Environmentally appropriate social behavior is critical for survival across the lifespan. To
support this flexible behavior, the brain must rapidly perform numerous computations taking …

Chronic stress deficits in reward behaviour co-occur with low nucleus accumbens dopamine activity during reward anticipation specifically

C Zhang, R Dulinskas, C Ineichen, A Greter… - Communications …, 2024 - nature.com
Whilst reward pathologies are major and common in stress-related neuropsychiatric
disorders, their neurobiology and treatment are poorly understood. Imaging studies in …

Stress deficits in reward behaviour are associated with and replicated by dysregulated amygdala-nucleus accumbens pathway function in mice

L Madur, C Ineichen, G Bergamini, A Greter… - Communications …, 2023 - nature.com
Reduced reward interest/learning and reward-to-effort valuation are distinct, common
symptoms in neuropsychiatric disorders for which chronic stress is a major aetiological …

Deep brain stimulation and neuropsychiatric anthropology–The “prosthetisability” of the lifeworld

C Ineichen, W Glannon - AJOB neuroscience, 2024 - Taylor & Francis
Abstract Deep Brain Stimulation (DBS) represents a key area of neuromodulation that has
gained wide adoption for the treatment of neurological and experimental testing for …

The impact of social defeat on basomedial amygdala neuronal activity in adult male rats

AC Ritger, CP Stickling, NC Ferrara - Behavioural Brain Research, 2023 - Elsevier
Social stressors negatively impact social function, and this is mediated by the amygdala
across species. Social defeat stress is an ethologically relevant social stressor in adult male …

Orphan receptor-GPR52 inverse agonist efficacy in ameliorating chronic stress-related deficits in reward motivation and phasic accumbal dopamine activity in mice

C Zhang, D Kúkeľová, H Sigrist, B Hengerer… - Translational …, 2024 - nature.com
Reward processing dysfunctions eg, anhedonia, apathy, are common in stress-related
neuropsychiatric disorders including depression and schizophrenia, and there are currently …

Multisensory integration of social signals by a pathway from the basal amygdala to the auditory cortex in maternal mice

AC Nowlan, J Choe, H Tromblee, C Kelahan… - Current Biology, 2025 - cell.com
Social encounters are inherently multisensory events, yet how and where social cues of
distinct sensory modalities merge and interact in the brain is poorly understood. When their …

[HTML][HTML] Structural covariance, topological organization, and volumetric features of amygdala subnuclei in posttraumatic stress disorder

EM Haris, RA Bryant, MS Korgaonkar - NeuroImage: Clinical, 2024 - Elsevier
The amygdala is divided into functional subnuclei which have been challenging to
investigate due to functional magnetic resonance imaging (MRI) limitations in mapping small …

A SMARTR workflow for multi-ensemble atlas mapping and brain-wide network analysis

M Jin, SO Ogundare, M Lanio, S Sorid, AR Whye… - BioRxiv, 2024 - pmc.ncbi.nlm.nih.gov
In the last decade, activity-dependent strategies for labelling multiple immediate early gene
(IEG) ensembles in mice have generated unprecedented insight into the mechanisms of …

Engagement of basal amygdala‐nucleus accumbens glutamate neurons in the processing of rewarding or aversive social stimuli

G Poggi, G Bergamini, R Dulinskas… - European Journal of …, 2024 - Wiley Online Library
Basal amygdala (BA) neurons projecting to nucleus accumbens (NAc) core/shell are
primarily glutamatergic and are integral to the circuitry of emotional processing. Several …