Context.—Controversies and uncertainty persist in prostate cancer grading. Objective.—To
update grading recommendations. Data Sources.—Critical review of the literature along with …

Simple Summary Although epithelial-to-mesenchymal transition (EMT) is a well-known
cellular process involved during normal embryogenesis and wound healing, it also has a …

PURPOSE This guideline provides recommendations for available tissue-based prostate
cancer biomarkers geared toward patient selection for active surveillance, identification of …

Purpose Kaempferol is a natural flavonoid that has been reported to be active against many
cancers, including prostate cancer, breast cancer and colon cancer. In our previous study …

Prostate cancer (CaP) remains the second leading cause of cancer deaths in Western men.
These deaths occur because metastatic CaP acquires resistance to available treatments …

Background Epigenetic modifiers, such as methyltransferases, play crucial roles in the
regulation of many biological processes, including development, cancer and multiple …

Aberrant activation of Ras/Raf/mitogen-activated protein kinase (MAPK) signaling is
frequently linked to metastatic prostate cancer (PCa); therefore, the characterization of …

Objective To investigate the value of whole-lesion texture analysis on preoperative
gadoxetic acid enhanced magnetic resonance imaging (MRI) for predicting tumor Ki-67 …

Standard clinical parameters fail to accurately differentiate indolent from aggressive prostate
cancer. Our previous studies showed that immunohistochemical testing for Ki-67 improved …

Chromatin modifiers and their implications in oncogenesis have been an exciting area of
cancer research. These are enzymes that modify chromatin via post-translational …