Transdermal delivery of encapsulated drugs

SS Mitragotri, D Blankschtein, RS Langer - US Patent 5,814,599, 1998 - Google Patents
Applications of low-frequency (20 KHz) ultrasound enhances transdermal transport of high-
molecular weight proteins. This method includes a simultaneous application of ultrasound …

Charged lipids and uses for the same

EC Unger - US Patent 6,120,751, 2000 - Google Patents
PORPENFLTBBHSG-MGBGTMOVSA-N 1, 2-dihexadecanoyl-sn-glycerol-3-phosphate
Chemical compound CCCCCCCCCCCCCCCC (= O) OC [C@ H](COP (O)(O)= O) OC (= O) …

Ultrasound catheter with cavitation promoting surface

D Hansmann, A Soltani - US Patent App. 11/402,626, 2006 - Google Patents
In one embodiment of the present invention, a method of applying ultrasonic energy to a
treatment site within a patient's vasculature comprises positioning an ultrasound radiating …

Apparatus and methods for ultrasonically enhanced fluid delivery

AF Brisken - US Patent 5,735,811, 1998 - Google Patents
The presentinvention relates generally to medical devices and methods. More particularly,
the present invention relates to apparatus and methods for the ultrasonically enhanced …

Apparatus and method for the treatment of tissue with ultrasound energy by direct contact

E Babaev - US Patent 7,431,704, 2008 - Google Patents
Apparatus and method for the treatment of tissue, such as hard and soft tissues, wounds,
tumors, muscles, and cartilage, through the direct contact of ultrasound energy is disclosed …

Ultrasound Therapy System

A Soltani, A Prokop - US Patent App. 11/739,629, 2007 - Google Patents
In one embodiment of the present invention, a system for treating an occlusion Within a
patient's vasculature With ultrasonic energy comprises a catheter con? gured to be passed …

Targeted gas and gaseous precursor-filled liposomes

EC Unger, TA Fritz, T Matsunaga… - US Patent …, 2000 - Google Patents
Methods of and apparatus for preparing temperature acti vated gaseous precursor-? lled
liposomes are described. Gas eous precursor-? lled liposomes prepared by these methods …

Effect of electric field and ultrasound for transdermal drug delivery

J Kost, U Pliquett, SS Mitragotri, RS Langer… - US Patent …, 2000 - Google Patents
Transdermal transport of molecules during Sonophoresis (delivery or extraction) can be
further enhanced by appli cation of an electric field, for example, electroporation or …

Catheters comprising bending transducers and methods for their use

AF Brisken - US Patent 5,931,805, 1999 - Google Patents
57 ABSTRACT A catheter comprises a catheter body having a bending plate transducer
disposed at or near its distal end. The bending plate transducer is typically a unimorph …

Apparatus and methods for ultrasonically enhanced intraluminal therapy

AF Brisken - US Patent 5,725,494, 1998 - Google Patents
An ultrasonic catheter comprises a catheter body having a resonantly vibrating assembly at
its distal end. The reso nantly vibrating assembly comprises a tail mass, an interface …