The ATP-sensitive potassium channels and their regulatory subunits, sulfonylurea receptor 1
(SUR1/Kir6. 2) and SUR2/Kir6. 1, contribute to the pathophysiology of pulmonary …

Functional neuroendocrine neoplasms (NENs) are those associated with specific symptoms
related to the hormonal secretion of the NENs. Although less than 25% of NENs are …

Vascular smooth muscle ATP-sensitive potassium (KATP) channels play critical roles in
modulating vascular tone and thus represent important drug targets for diverse …

Objective Transient hyperinsulinism (THI) is the most common form of recurrent
hypoglycaemia in neonates beyond the first week of life. Although self‐resolving, treatment …

Diazoxide is one of the FDA-approved pharmacologic treatments for hyperinsulinemic
hypoglycemia, however, its adverse effects in infants are not well described. We reported a …

Discussion We posit the patient was predisposed to hyperglycemia based on elevated
diazoxide serum concentration. We hypothesize severe dehydration led to renal impairment …

Neonatal hypoglycemia (NH) is broadly defined as a low plasma glucose concentration that
elicits hypoglycemia-induced impaired brain function. To date, no universally accepted …

Objectives Congenital syphilis can cause severe morbidities such as hydrops fetalis,
preterm birth, low birth weight, hepatosplenomegaly, pneumonia, hypoglycemia, etc., and …

Insulinomas are rare neuroendocrine neoplasms and causes of hypoglycemia. They present
with neuroglycopenic symptoms, including confusion and seizures. Suspected diagnosis …

BACKGROUND: With increasing use of diazoxide for hyperinsulinemic hypoglycemia (HH),
reporting of serious side effects of diazoxide such as pulmonary hypertension (PHT) …