Microglia have been recently shown to manifest a very interesting phenotypical
heterogeneity across different regions in the mammalian central nervous system (CNS) …

Microglia are ramified cells that exhibit highly motile processes, which continuously survey
the brain parenchyma and react to any insult to the CNS homeostasis. Although microglia …

Microglial cells are the resident macrophages of the central nervous system (CNS) and are
mainly known for their roles in neuropathologies. However, major recent developments have …

Chemokines are known to be immunoregulatory proteins involved not only in lymphocyte
chemotaxis to the site of inflammation, but also in neuromodulation, neurogenesis, and …

Converging lines of evidence from basic science and clinical studies suggest a relationship
between maternal immune activation (MIA) and neurodevelopmental disorders such as …

It is widely held that schizophrenia involves an active process of peripheral inflammation that
induces or reflects brain inflammation with activation of microglia, the brain's resident …

Synapses are well known as the main structures responsible for transmitting information
through the release and recognition of neurotransmitters by pre-and post-synaptic neurons …

Schizophrenia is a psychiatric disorder with significant impact on individuals and society.
The current pharmacologic treatment, which principally alleviates psychosis, is focused on …

Microglia, the immune cells of the brain, are important for neurodevelopment and have been
hypothesized to play a role in the pathogenesis of schizophrenia (SCZ). Although previous …

Microglia cells are the unique residential macrophages of the central nervous system (CNS).
They have a special origin, as they derive from the embryonic yolk sac and enter the …