GABAergic neuronal lineage development determines clinically actionable targets in diffuse hemispheric glioma, H3G34-mutant

I Liu, GAV Cruzeiro, L Bjerke, RF Rogers, Y Grabovska… - Cancer Cell, 2024 - cell.com
Diffuse hemispheric gliomas, H3G34R/V-mutant (DHG-H3G34), are lethal brain tumors
lacking targeted therapies. They originate from interneuronal precursors; however …

Multi-scale signaling and tumor evolution in high-grade gliomas

J Liu, S Cao, KJ Imbach, MA Gritsenko, TSM Lih… - Cancer cell, 2024 - cell.com
Although genomic anomalies in glioblastoma (GBM) have been well studied for over a
decade, its 5-year survival rate remains lower than 5%. We seek to expand the molecular …

Integrative multi-omics characterization reveals sex differences in glioblastoma

B Jang, D Yoon, JY Lee, J Kim, J Hong, H Koo… - Biology of sex …, 2024 - Springer
Background Glioblastoma (GBM) is the most common and lethal primary brain tumor in
adults, with limited treatment modalities and poor prognosis. Recent studies have …

DNA nanomachine‐driven chemodynamic therapy against glioblastoma

X Li, Y Lan, X Fu, X Luo, J Chen, W Zhang, B Zuo… - …, 2024 - Wiley Online Library
Chemodynamic therapy (CDT) has shown promising antitumor effects in various malignant
tumors. However, its application for glioblastoma (GBM) is significantly hindered by the …

Integrated Proteogenomics Uncover Mechanisms of Glioblastoma Evolution, Pointing to Novel Therapeutic Targets

J Li, LK Shih, DJ Brat - Cancer Research, 2024 - AACR
Nearly all glioblastoma (GBM) patients relapse following standard treatment and eventually
succumb to disease. While large-scale, integrated multiomic studies have tremendously …

Exploring the neuropsychological basis of behavioral contagion during learning about another agent's social preferences: Evidence from an ERP study

M Deldoost, R Khosrowabadi, M Kamiński - Acta Neurobiologiae …, 2024 - ane.pl
Social contagion is a pervasive phenomenon and an important social influence that involves
the rapid dissemination (propagation) of behaviors, attitudes, emotions, or ideas from one …

Analysis of gliomas DNA methylation: Assessment of pre-analytical variables.

K Bomsztyk, D Mar, O Denisenko, S Powell, M Vishnoi… - bioRxiv, 2024 - biorxiv.org
Precision oncology is driven by molecular biomarkers. For glioblastoma multiforme (GBM),
the most common malignant adult primary brain tumor, O6-methylguanine-DNA …