Breathing is a vital rhythmic motor behavior with a surprisingly broad influence on the brain
and body. The apparent simplicity of breathing belies a complex neural control system, the …

The brain is organized as a network of highly specialized networks of spiking neurons. To
exploit such a modular architecture for computation, the brain has to be able to regulate the …

Gene expression studies suggest that differential ion channel expression contributes to
differences in rodent versus human neuronal physiology. We tested whether h-channels …

Itch and pain are distinct unpleasant sensations that can be triggered from the same
receptive fields in the skin, raising the question of how pruriception and nociception are …

Electrically activating mechanoreceptive afferents inhibits pain. However, paresthesia
evoked by spinal cord stimulation (SCS) at 40–60 Hz becomes uncomfortable at high pulse …

Firing rate is an important means of encoding information in the nervous system. To reliably
encode a wide range of signals, neurons need to achieve a broad range of firing …

Despite advances in experimental and theoretical neuroscience, we are still trying to identify
key biophysical details that are important for characterizing the operation of brain circuits …

Relaying neural signals between cortical areas is central to cognition and sensory
processing. The temporal coordination of activity in a source population has been suggested …

We assessed the mechanism of mammalian breathing rhythmogenesis in the preBötzinger
complex (preBötC) in vitro, where experimental tests remain inconsistent with hypotheses of …

The field of invasive brain-machine interfaces (BMIs) is typically associated with
neuroprosthetic applications aiming to recover loss of motor function. However, BMIs also …