[HTML][HTML] ME/CFS and Long COVID share similar symptoms and biological abnormalities: road map to the literature

AL Komaroff, WI Lipkin - Frontiers in Medicine, 2023 - frontiersin.org
Some patients remain unwell for months after “recovering” from the acute COVID-19. They
develop persistent fatigue, cognitive problems, headaches, disrupted sleep, myalgias and …

[HTML][HTML] Causal association of epigenetic aging and COVID-19 severity and susceptibility: a bidirectional Mendelian randomization study

W Xu, F Zhang, Y Shi, Y Chen, B Shi, G Yu - Frontiers in Medicine, 2022 - frontiersin.org
Observational data from China, the United States, France, and Italy suggest that aging is an
adverse COVID-19 outcome risk factor, with older patients having a higher severity and …

[PDF][PDF] Interactomics: Dozens of Viruses, Co-evolving With Humans, Including the Influenza A Virus, may Actively Distort Human Aging

J Teulière, C Bernard, H Bonnefous… - Molecular biology …, 2023 - academic.oup.com
Some viruses (eg, human immunodeficiency virus 1 and severe acute respiratory syndrome
coronavirus 2) have been experimentally proposed to accelerate features of human aging …

[HTML][HTML] Epidemiological and clinical features of SARS-CoV-2 variants circulating between April–December 2021 in Italy

A Lai, A Bergna, C Della Ventura, S Menzo… - Viruses, 2022 - mdpi.com
SARS-CoV-2 is constantly evolving, leading to new variants. We analysed data from 4400
SARS-CoV-2-positive samples in order to pursue epidemiological variant surveillance and …

[HTML][HTML] A review of the main genetic factors influencing the course of COVID-19 in Sardinia: the role of human leukocyte antigen-G

S Mocci, R Littera, L Chessa, M Campagna… - Frontiers in …, 2023 - frontiersin.org
Introduction A large number of risk and protective factors have been identified during the
SARS-CoV-2 pandemic which may influence the outcome of COVID-19. Among these …

[HTML][HTML] Transcriptional insights of oxidative stress and extracellular traps in lung tissues of fatal COVID-19 cases

A Hosseini, D Stojkov, T Fettrelet, R Bilyy… - International journal of …, 2023 - mdpi.com
Neutrophil extracellular traps (NETs) and oxidative stress are considered to be beneficial in
the innate immune defense against pathogens. However, defective clearance of NETs in the …

[HTML][HTML] Cellular senescence is a key mediator of lung aging and susceptibility to infection

BL Torrance, L Haynes - Frontiers in immunology, 2022 - frontiersin.org
Aging results in systemic changes that leave older adults at much higher risk for adverse
outcomes following respiratory infections. Much work has been done over the years to …

[HTML][HTML] Severe COVID-19 patients exhibit elevated levels of autoantibodies targeting cardiolipin and platelet glycoprotein with age: a systems biology approach

DLM Fonseca, IS Filgueiras, AHC Marques, E Vojdani… - npj Aging, 2023 - nature.com
Age is a significant risk factor for the coronavirus disease 2019 (COVID-19) severity due to
immunosenescence and certain age-dependent medical conditions (eg, obesity …

[HTML][HTML] Effective virus-specific T-cell therapy for high-risk SARS-CoV-2 infections in hematopoietic stem cell transplant recipients: initial case studies and literature …

L Gopcsa, M Réti, H Andrikovics, I Bobek, G Bekő… - GeroScience, 2024 - Springer
The COVID-19 pandemic has exacerbated mortality rates among immunocompromised
patients, accentuating the need for novel, targeted therapies. Transplant recipients, with their …

[HTML][HTML] Virus-induced membrane fusion in neurodegenerative disorders

C Osorio, A Sfera, JJ Anton, KG Thomas… - Frontiers in Cellular …, 2022 - frontiersin.org
A growing body of epidemiological and research data has associated neurotropic viruses
with accelerated brain aging and increased risk of neurodegenerative disorders. Many …