Oral Diseases (2011) 17, 345–354 For the past two decades, salivary diagnostic
approaches have been developed to monitor oral diseases such as periodontal diseases …

Purpose: Multiplexing assay of biomarkers at the point-of-care is an elusive goal for
molecular diagnostics. Experimental Design: Here, we report an electrochemical (EC) …

Purpose Up to 25% of patients with node-negative colorectal cancer (CRC) on conventional
histopathologic analysis ultimately die of recurrent disease. We performed a systematic …

PURPOSE: Approximately 30% of patients with American Joint Committee on Cancer stage I
or II colorectal cancer (CRC) develop systemic disease. We hypothesized that multimarker …

Antitumor immunotherapy for colorectal cancer has been studied at the bench and bedside
for decades. Some clinical trials of cancer immunotherapy have demonstrated a potential …

Guanylin, uroguanylin, and the bacterial heat-stable enterotoxin (ST) peptides comprise a
new family of cyclic guanosine 3′-5′ monophosphate (cGMP)-regulating agonists. The …

The effects of Escherichia coli heat-stable enterotoxin (ST) and uroguanylin were examined
on the proliferation of T84 and Caco2 human colon carcinoma cells that express guanylyl …

The role of ion channels in carcinogenesis and tumor progression remains unclear. We
have used suppression subtractive hybridization of mRNA from paired normal colon …

Gastrointestinal (GI) tumors continue to be major causes of cancer-related mortality, in part,
reflecting metastases that escape detection by histopathology. Moreover, although …

Guanylate cyclase C (GUCY2C) is a transmembrane receptor expressed on the luminal
aspect of the intestinal epithelium. Its ligands include bacterial heat-stable enterotoxins …