Death-associated protein kinase 1 as a therapeutic target for Alzheimer's disease
T Zhang, BM Kim, TH Lee - Translational neurodegeneration, 2024 - Springer
Alzheimer's disease (AD) is the most prevalent form of dementia in the elderly and
represents a major clinical challenge in the ageing society. Neuropathological hallmarks of …
represents a major clinical challenge in the ageing society. Neuropathological hallmarks of …
[HTML][HTML] ATG8 in Single Membranes: Fresh Players of Endocytosis and Acidic Organelle Quality Control in Cancer, Neurodegeneration, and Inflammation
BB Wang, MP Apaja - Biochemical and Biophysical Research …, 2025 - Elsevier
Ubiquitin-like autophagy-related gene ATG8 proteins are typically associated with
degradative quality control via canonical double-membrane macro-autophagosomes in the …
degradative quality control via canonical double-membrane macro-autophagosomes in the …
SIRT2 Promotes NLRP3-Mediated Microglia Pyroptosis and Neuroinflammation via FOXO3a Pathway After Subarachnoid Hemorrhage
JQ Sun, B Sheng, S Gao, XZ Liu, Y Cui… - Journal of …, 2024 - Taylor & Francis
Purpose This study primarily elucidating the specific mechanism of SIRT2 on
neuroinflammation and microglial pyroptosis in a mouse model of SAH. Patients and …
neuroinflammation and microglial pyroptosis in a mouse model of SAH. Patients and …
V-ATPase B2 promotes microglial phagocytosis of myelin debris by inactivating the MAPK signaling pathway
Y Li, Y Dai, L Chu - Neuropeptides, 2024 - Elsevier
Microglial phagocytosis of myelin debris is a crucial process for promoting myelin
regeneration in conditions such as multiple sclerosis (MS). Vacuolar-ATPase B2 (V-ATPase …
regeneration in conditions such as multiple sclerosis (MS). Vacuolar-ATPase B2 (V-ATPase …
6-姜烯酚通过miRNA-26a-5p/DAPK1 减轻大鼠脑缺血再灌注损伤.
饶欧阳， 李世欣， 朱宁， 周航向… - Science …, 2024 - search.ebscohost.com
摘要为探究6-姜烯酚(6-Shogaol, 6-SH) 对大鼠脑缺血再灌注损伤(cerebral ischemia-
reperfusion injury, CIRI) 的保护作用, 采用分子对接观察6-SH 能否自发性结合microRNA-26a …
reperfusion injury, CIRI) 的保护作用, 采用分子对接观察6-SH 能否自发性结合microRNA-26a …
Mapping of catecholaminergic denervation, neurodegeneration, and inflammation in 6-OHDA-treated Parkinson's disease mice
M Santoro, RK Lam, SE Blumenfeld, W Tan, P Ciari… - 2024 - researchsquare.com
Efforts to develop disease-modifying treatments for Parkinson's disease (PD) have been
hindered by the lack of animal models replicating all hallmarks of PD and the insufficient …
hindered by the lack of animal models replicating all hallmarks of PD and the insufficient …
Tremella fuciformis polysaccharides alleviate early brain injury in experimental subarachnoid hemorrhage by inhibiting the KDR-mediated P38 MAPK/NF-κB pathway
Y Wan, X Chen, Z Cheng, L Fan, D Yang, B Chen… - 2024 - researchsquare.com
Background Subarachnoid hemorrhage is associated with high mortality and morbidity
rates. In its early stages, the substantial influx of blood into the subarachnoid space triggers …
rates. In its early stages, the substantial influx of blood into the subarachnoid space triggers …