Immune-mediated inflammatory diseases (IMIDs), such as spondyloarthritis (SpA), psoriasis,
Crohn's disease (CD), and rheumatoid arthritis (RA) remain challenging illnesses. They …

Juvenile idiopathic arthritis (JIA) is a term that collectively refers to a group of chronic
childhood arthritides, which together constitute the most common rheumatic condition in …

Objective To evaluate the efficacy and safety of adalimumab (ADA) versus hyaluronic acid
(HA) by intra-articular injection for moderate to severe knee osteoarthritis. Methods Fifty-six …

Inflammatory bowel diseases (IBD) are chronic disorders of the gastrointestinal tract that
have been linked to microbiome dysbiosis and immune system dysregulation. We …

This study aimed to explore the dynamic interactions between 32 cytokines and biomarkers
in Psoriatic Arthritis (PsA) patients to compare cytokine signatures of treatment responders …

Periodontitis is a chronic inflammatory disease that affects the tissues surrounding the teeth,
including the gums and the bones supporting the teeth. Early detection and intervention are …

TNF-α inhibitors have demonstrated efficacy both as monotherapy and in combination with
disease-modifying anti-rheumatic drugs (DMARDs) in the treatment of chronic inflammatory …

Abstract Measurement of Tumour Necrosis Factor alpha (TNF-α) in peripheral blood is a
useful tool to assess inflammatory responses in a large range of diseases. One of the major …

Hypogonadism in adolescents is a clinical syndrome resulting from failure to produce
physiological concentrations of sex steroid hormones with accompanying symptoms, such …

An autoimmune inflammatory disease, rheumatoid arthritis (RA), predominantly affects the
synovium joint lining, augmenting disability, early mortality, and socioeconomic difficulty …