Articular cartilage defects bring about disability and worldwide socioeconomic loss,
therefore, articular cartilage repair and regeneration is recognized as a global issue …

The concept of three-dimensional (3D) cell culture has been proposed to maintain cellular
morphology and function as in vivo. Among different approaches for 3D cell culture …

Microscale cell carriers have recently garnered enormous interest in repairing tissue defects
by avoiding substantial open surgeries using implants for tissue regeneration. In this study …

Over the past two decades, evidence has emerged for the existence of a distinct population
of endogenous progenitor cells in adult articular cartilage, predominantly referred to as …

Different types of biomaterials, processed into different shapes, have been proposed as
temporary support for cells in tissue engineering (TE) strategies. The manufacturing …

Stirred microcarrier (MC) culture has been suggested as the method of choice for supplying
large volumes of mesenchymal stem cells (MSCs) for bone tissue engineering. In this study …

For tissue regeneration or repair, a suitable temporary scaffold needs to be constructed for
delivering regenerative cells to damaged or diseased tissue. Scaffold types are currently …

Microcarrier cultures have been shown to allow extensive cell expansion of tissue
engineering relevant cells, such as chondrocytes, while maintaining their phenotype. Our …

For the continuous and fast expansion of mesenchymal stem cells (MSCs), microcarriers
have gained increasing interest. The aim of this study was to evaluate the growth and …

Embryonic stem (ES) cells have the ability to differentiate in vitro into a wide variety of cell
types with potential applications for tissue regeneration. However, a large number of cells …