Alternative splicing (AS) creates multiple mRNA transcripts from a single gene. While AS is
known to contribute to gene regulation and proteome diversity in animals, the study of its …

Serine/arginine rich splicing factor 3 (SRSF3) is an important multi-functional splicing factor,
and has attracted increasing attentions in the past thirty years. The importance of SRSF3 is …

Background Mounting epidemiological evidence supports a role for phosphatase and tensin
homologue (PTEN)-T cell leukaemia 1 (Tcl1) signalling deregulation in …

Numerous mechanisms involved in promoting cancer cell survival under nutrient starvation
have been described. Long noncoding RNAs (lncRNAs) have emerged as critical players in …

Carcinoembryonic antigen-related cell adhesion molecule-1 (CEACAM1) is expressed in a
variety of cell types and is implicated in carcinogenesis. Alternative splicing of CEACAM1 …

Background Urinary bladder cancer is one of the most fatal and expensive diseases of
industrialized world. Despite the strenuous efforts, no seminal advances have been …

Abstract Glucose-6-phosphate dehydrogenase (G6PD) is critical to the maintenance of
NADPH pool and redox homeostasis. Conventionally, G6PD deficiency has been …

Expression of G6PD is controlled by changes in the degree of splicing of the G6PD mRNA in
response to nutrients in the diet. This regulation involves an exonic splicing enhancer (ESE) …

Precursor mRNA (pre-mRNA) splicing is a critical step in gene expression that results in the
removal of intronic sequences from immature mRNA, leading to the production of mature …

RNA-RNA interactions play a crucial role in regulating gene expression and various
biological processes, but identifying these interactions on a transcriptomic scale remains a …