Uterine leiomyosarcoma (uLMS) is the most common subtype of uterine sarcomas. They
have a poor prognosis with high rates of recurrence and metastasis. The five-year survival …

Uterine fibroids (UFs) are the most common benign tumors of female genital diseases,
unlike uterine leiomyosarcoma (LMS), a rare and aggressive uterine cancer. This narrative …

Leiomyosarcoma (LMS) is the most common uterine sarcoma. Although the disease is
relatively rare, it is responsible for considerable mortality due to frequent metastasis and …

BACKGROUND Uterine smooth muscle tumors (USMTs) constitute a group of histologic,
genetic, and clinical heterogeneous tumors that include at least 6 major histologically …

Uterine leiomyosarcomas (uLMS) are rare, aggressive malignancies for which limited
treatment options are available. To gain novel molecular insights into uLMS and identify …

The diagnosis and management of uterine smooth muscle tumors with uncertain malignant
potential (STUMP) is often challenging, and genomic data on these lesions as well as on …

Mutations in exon 2 of the MED12 gene have been reported in 50% to 70% of uterine
leiomyomas. To determine the frequency of MED12 mutations in various types of smooth …

CEMIP (KIAA1199) was identified as migratory indicator protein which had been crudely
studied in the last decade. Firstly its mutation site was reported to cause hearing loss due to …

Leiomyosarcoma (LMS) is a soft tissue sarcoma of smooth muscle origin that can arise in
multiple anatomical sites and is broadly classified as extra-uterine LMS or uterine LMS …

Abstract microRNAs are small non-coding RNAs of~ 22 nucleotides that function at post-
transcriptional level as negative regulators of gene expression. Aberrant expression of …