Persistent organochlorinated pesticides and mechanisms of their toxicity

EJ Mrema, FM Rubino, G Brambilla, A Moretto… - Toxicology, 2013 - Elsevier
Persistent organic pollutants comprised of organic chemicals like polychlorinated biphenyls,
dibenzo-p-dioxins, dibenzofurans and organochlorinated pesticides which have many …

Review of the toxicology of chlorpyrifos with an emphasis on human exposure and neurodevelopment

DL Eaton, RB Daroff, H Autrup, J Bridges… - Critical reviews in …, 2008 - Taylor & Francis
This review examines the large body of toxicological and epidemiological information on
human exposures to chlorpyrifos, with an emphasis on the controversial potential for …

Respiratory effects of air pollution on children

FC Goldizen, PD Sly, LD Knibbs - Pediatric pulmonology, 2016 - Wiley Online Library
A substantial proportion of the global burden of disease is directly or indirectly attributable to
exposure to air pollution. Exposures occurring during the periods of organogenesis and …

Causes of genome instability: the effect of low dose chemical exposures in modern society

SAS Langie, G Koppen, D Desaulniers… - …, 2015 - academic.oup.com
Genome instability is a prerequisite for the development of cancer. It occurs when genome
maintenance systems fail to safeguard the genome's integrity, whether as a consequence of …

Effect of prenatal exposure to airborne polycyclic aromatic hydrocarbons on neurodevelopment in the first 3 years of life among inner-city children

FP Perera, V Rauh, RM Whyatt, WY Tsai… - Environmental …, 2006 - ehp.niehs.nih.gov
Our prospective cohort study of nonsmoking African-American and Dominican mothers and
children in New York City is evaluating the role of prenatal exposure to urban pollutants …

Environmental epigenetics and its implication on disease risk and health outcomes

SM Ho, A Johnson, P Tarapore, V Janakiram… - ILAR …, 2012 - academic.oup.com
This review focuses on how environmental factors through epigenetics modify disease risk
and health outcomes. Major epigenetic events, such as histone modifications, DNA …

Oxidative stress in environmental-induced carcinogenesis

S Mena, A Ortega, JM Estrela - Mutation Research/Genetic Toxicology and …, 2009 - Elsevier
Reactive oxygen species (ROS) are the more abundant free radicals in nature and have
been related with a number of tissue/organ injuries induced by xenobiotics, ischemia …

Environmental exposures and adverse pregnancy outcomes: a review of the science

KP Stillerman, DR Mattison, LC Giudice… - Reproductive …, 2008 - journals.sagepub.com
To better understand the science linking environmental contaminants exposures with
adverse pregnancy outcomes, we reviewed the relevant epidemiologic literature. We …

BPDE exposure promotes trophoblast cell pyroptosis and induces miscarriage by up-regulating lnc-HZ14/ZBP1/NLRP3 axis

R Wang, X Xu, J Yang, W Chen, J Zhao, M Wang… - Journal of hazardous …, 2023 - Elsevier
Abstract Environmental Benzo (a) pyrene (BaP) and its ultimate metabolite BPDE (benzo (a)
pyrene-7, 8-dihydrodiol-9, 10-epoxide) are typical persistent organic pollutants and …

polycyclic aromatic hydrocarbons (PAHs)—action on placental function and health risks in future life of newborns

E Drwal, A Rak, EL Gregoraszczuk - Toxicology, 2019 - Elsevier
Polycyclic aromatic hydrocarbons (PAHs) are common environmental pollutants, which are
released as products of incomplete combustion processes. Harmful effects of PAHs …