[HTML][HTML] Oncological role of HMGA2
S Zhang, Q Mo, X Wang - International journal of …, 2019 - spandidos-publications.com
The high mobility group A2 (HMGA2) protein is a non‑histone architectural transcription
factor that modulates the transcription of several genes by binding to AT‑rich sequences in …
factor that modulates the transcription of several genes by binding to AT‑rich sequences in …
Self-inactivating lentivirus vector for safe and efficient in vivo gene delivery
R Zufferey, T Dull, RJ Mandel, A Bukovsky… - Journal of …, 1998 - Am Soc Microbiol
In vivo transduction of nondividing cells by human immunodeficiency virus type 1 (HIV-1)-
based vectors results in transgene expression that is stable over several months. However …
based vectors results in transgene expression that is stable over several months. However …
The tumor suppressor microRNA let-7 represses the HMGA2 oncogene
HMGA2, a high-mobility group protein, is oncogenic in a variety of tumors, including benign
mesenchymal tumors and lung cancers. Knockdown of Dicer in HeLa cells revealed that the …
mesenchymal tumors and lung cancers. Knockdown of Dicer in HeLa cells revealed that the …
Mutation responsible for the mouse pygmy phenotype in the developmentally regulated factor HMGI-C
X Zhou, KF Benson, HR Ashar, K Chada - Nature, 1995 - nature.com
GROWTH is one of the fundamental aspects in the development of an organism. Classical
genetic studies have isolated four viable, spontaneous mouse mutants1 disrupted in growth …
genetic studies have isolated four viable, spontaneous mouse mutants1 disrupted in growth …
Transforming growth factor-β employs HMGA2 to elicit epithelial–mesenchymal transition
S Thuault, U Valcourt, M Petersen… - The Journal of cell …, 2006 - rupress.org
Epithelial–mesenchymal transition (EMT) occurs during embryogenesis, carcinoma
invasiveness, and metastasis and can be elicited by transforming growth factor-β (TGF-β) …
invasiveness, and metastasis and can be elicited by transforming growth factor-β (TGF-β) …
High-mobility-group chromosomal proteins: architectural components that facilitate chromatin function
M Bustin, R Reeves - Progress in nucleic acid research and molecular …, 1996 - Elsevier
Publisher Summary This chapter summarizes recent information on the function of high-
mobility-group (HMG) proteins. Advances in this field were made primarily by elucidating the …
mobility-group (HMG) proteins. Advances in this field were made primarily by elucidating the …
Updates on cytogenetics and molecular genetics of bone and soft tissue tumors:: Ewing sarcoma and peripheral primitive neuroectodermal tumors
AA Sandberg, JA Bridge - Cancer genetics and cytogenetics, 2000 - Elsevier
Cytogenetics of Bone and Soft Tissue Tumors [1]. In view of the remarkable developments in
this field since 1994, both in the cytogenetic and particularly in the molecular genetic …
this field since 1994, both in the cytogenetic and particularly in the molecular genetic …
Molecular biology of HMGA proteins: hubs of nuclear function
R Reeves - Gene, 2001 - Elsevier
Members of the HMGA (aka HMGI/Y) family of 'high mobility group'(HMG) proteins
participate in a wide variety of nuclear processes ranging from chromosome and chromatin …
participate in a wide variety of nuclear processes ranging from chromosome and chromatin …
HMGI/Y proteins: flexible regulators of transcription and chromatin structure
R Reeves, L Beckerbauer - Biochimica et Biophysica Acta (BBA)-Gene …, 2001 - Elsevier
The mammalian HMGI/Y (HMGA) non-histone proteins participate in a wide variety of
cellular processes including regulation of inducible gene transcription, integration of …
cellular processes including regulation of inducible gene transcription, integration of …