A comprehensive overview of metaplastic breast cancer: clinical features and molecular aberrations

TP Reddy, RR Rosato, X Li, S Moulder… - Breast Cancer …, 2020 - Springer
Metaplastic breast cancer (MpBC) is an exceedingly rare breast cancer variant that is
therapeutically challenging and aggressive. MpBC is defined by the histological presence of …

The interactions of obesity, inflammation and insulin resistance in breast cancer

DP Rose, PJ Gracheck, L Vona-Davis - Cancers, 2015 - mdpi.com
Obese postmenopausal women have an increased breast cancer risk, the principal
mechanism for which is elevated estrogen production by adipose tissue; also, regardless of …

[HTML][HTML] A multi-targeted approach to suppress tumor-promoting inflammation

AK Samadi, A Bilsland, AG Georgakilas… - Seminars in cancer …, 2015 - Elsevier
Cancers harbor significant genetic heterogeneity and patterns of relapse following many
therapies are due to evolved resistance to treatment. While efforts have been made to …

Investigation of potential breath biomarkers for the early diagnosis of breast cancer using gas chromatography–mass spectrometry

J Li, Y Peng, Y Liu, W Li, Y Jin, Z Tang, Y Duan - Clinica chimica acta, 2014 - Elsevier
Background Breast cancer (BC) remains the most commonly diagnosed malignancy in
women. We investigated 4 straight aldehydes in the exhaled breath as potential early BC …

Strategies for the development of selenium-based anticancer drugs

P Collery - Journal of Trace Elements in Medicine and Biology, 2018 - Elsevier
Many experimental models demonstrated that inorganic and organic selenium (Se)
compounds may have an anticancer activity. However, large clinical studies failed to …

Tumor secretion of CCL22 activates intratumoral Treg infiltration and is independent prognostic predictor of breast cancer

YQ Li, FF Liu, XM Zhang, XJ Guo, MJ Ren, L Fu - PloS one, 2013 - journals.plos.org
It has been reported that dense intratumoral infiltration of Foxp3+ Tregs (Tregs) was an
independent factor for poor prognosis of breast cancer (BC) patients. However, the cytokines …

Breast cancer in Brazil: epidemiology and treatment challenges

AP Cecilio, ET Takakura, JJ Jumes… - … Cancer: Targets and …, 2015 - Taylor & Francis
Notwithstanding the advances in tumor research, diagnosis, and treatment, breast cancer is
still a challenge worldwide. This global burden of disease has been associated with …

Unraveling Biomarker Signatures in Triple-Negative Breast Cancer: A Systematic Review for Targeted Approaches

P Pastena, H Perera, A Martinino, W Kartsonis… - International Journal of …, 2024 - mdpi.com
Triple-negative breast cancer (TNBC) is one of the most aggressive subtypes of breast
cancer, marked by poor outcomes and dismal prognosis. Due to the absence of targetable …

Review of triple negative breast cancer and the impact of inducible nitric oxide synthase on tumor biology and patient outcomes

EM Walsh, MM Keane, DA Wink… - Critical Reviews™ in …, 2016 - dl.begellhouse.com
Triple negative breast cancers (TNBCs), which are defined as estrogen-receptor,
progesterone-receptor, and HER2-receptor negative, account for 10–20% of breast cancers …

Antitumor activity of a rhenium (I)-diselenoether complex in experimental models of human breast cancer

P Collery, A Mohsen, A Kermagoret, S Corre… - Investigational new …, 2015 - Springer
Summary Rhenium (I)-diselenother (Re-diselenoether) is a water soluble metal-based
compound, combining one atom of rhenium and two atoms of selenium. This compound has …