Contributions of the international plant science community to the fight against infectious diseases in humans—part 2: Affordable drugs in edible plants for endemic and …

W He, C Baysal, M Lobato Gomez… - Plant biotechnology …, 2021 - Wiley Online Library
The fight against infectious diseases often focuses on epidemics and pandemics, which
demand urgent resources and command attention from the health authorities and media …

Molecular Pharming for low and middle income countries

S Murad, S Fuller, J Menary, C Moore, E Pinneh… - Current opinion in …, 2020 - Elsevier
Interest in applications and benefits that Molecular Pharming might offer to Low and Middle
Income Countries has always been a potent driver for the research discipline, and a major …

In vitro and in vivo studies of plant-produced Atezolizumab as a potential immunotherapeutic antibody

K Rattanapisit, CJI Bulaon, R Strasser, H Sun… - Scientific Reports, 2023 - nature.com
Immune checkpoint inhibitors are a well-known class of immunotherapeutic drugs that have
been used for effective treatment of several cancers. Atezolizumab (Tecentriq) was the first …

Structural and In Vitro Functional Analyses of Novel Plant-Produced Anti-Human PD1 Antibody

K Rattanapisit, T Phakham, S Buranapraditkun… - Scientific reports, 2019 - nature.com
Immunotherapy has emerged as a promising and effective treatment for cancer. The
frequently used immunotherapy agents are immune checkpoint inhibitors, such as …

Immunological aspects of rabies: a literature review

ISS Katz, F Guedes, ER Fernandes… - Archives of …, 2017 - Springer
Rabies is a lethal disease caused by the neurotropic virus rabies virus (RABV), and it
remains an important public health problem globally. It is known that the host immune …

Efficiency Comparative Approach of Plant-Produced Monoclonal Antibodies against Rabies Virus Infection

B Lumlertdacha, B Mahong, K Rattanapisit, CJI Bulaon… - Vaccines, 2023 - mdpi.com
Rabies encephalitis is a fatal zoonotic viral disease caused by the neurotropic rabies virus. It
remains a major public health concern as it causes almost 100% fatality and has no effective …

Molecular farming for therapies and vaccines in Africa

TL Tsekoa, AA Singh, SG Buthelezi - Current opinion in biotechnology, 2020 - Elsevier
Highlights•Local manufacturing of protein-based vaccines and therapies in Africa is currently
limited.•Plant molecular farming is a promising technology solution for Africa.•Plant-made …

Impact of glycoengineering and antidrug antibodies on the anticancer activity of a plant‐made lectin‐Fc fusion protein

M Dent, KL Mayer, N Verjan Garcia… - Plant Biotechnology …, 2022 - Wiley Online Library
Plants are an efficient production platform for manufacturing glycoengineered monoclonal
antibodies and antibody‐like molecules. Avaren‐Fc (AvFc) is a lectin‐Fc fusion protein or …

Plant-made antibodies: properties and therapeutic applications

TV Komarova, EV Sheshukova… - Current Medicinal …, 2019 - ingentaconnect.com
Background: A cost-effective plant platform for therapeutic monoclonal antibody production
is both flexible and scalable. Plant cells have mechanisms for protein synthesis and …

Hydroponic Treatment of Nicotiana benthamiana with Kifunensine Modifies the N-glycans of Recombinant Glycoprotein Antigens to Predominantly Man9 High …

S Roychowdhury, YJ Oh, H Kajiura… - Frontiers in plant …, 2018 - frontiersin.org
Nicotiana benthamiana transient overexpression systems offer unique advantages for rapid
and scalable biopharmaceuticals production, including high scalability and eukaryotic post …