Transition-metal-catalyzed C–H bond activation for the formation of C–C bonds in complex molecules

JH Docherty, TM Lister, G Mcarthur, MT Findlay… - Chemical …, 2023 - ACS Publications
Site-predictable and chemoselective C–H bond functionalization reactions offer synthetically
powerful strategies for the step-economic diversification of both feedstock and fine …

Recent advances in metal‐catalyzed functionalization of indoles

K Urbina, D Tresp, K Sipps… - Advanced Synthesis & …, 2021 - Wiley Online Library
Indole is one of the most important heterocycles in organic synthesis, natural products, and
drug discovery. Recently, tremendous advances in the selective functionalization of indoles …

Electrochemically enabled, nickel-catalyzed dehydroxylative cross-coupling of alcohols with aryl halides

Z Li, W Sun, X Wang, L Li, Y Zhang… - Journal of the American …, 2021 - ACS Publications
As alcohols are ubiquitous throughout chemical science, this functional group represents a
highly attractive starting material for forging new C–C bonds. Here, we demonstrate that the …

Ruthenium (II)-catalyzed C–H bond activation and functionalization

PB Arockiam, C Bruneau, PH Dixneuf - Chemical reviews, 2012 - ACS Publications
The catalytic functionalization of unreactive C− H bonds has recently brought a revolution in
synthetic methodologies for the production of pharmaceuticals and natural products and for …

Dynamic kinetic cross-electrophile arylation of benzyl alcohols by nickel catalysis

P Guo, K Wang, WJ Jin, H Xie, L Qi… - Journal of the …, 2020 - ACS Publications
Catalytic transformation of alcohols via metal-catalyzed cross-coupling reactions is very
important, but it typically relies on a multistep procedure. We here report a dynamic kinetic …

Recent developments in ruthenium-catalyzed C–H arylation: Array of mechanistic manifolds

P Nareddy, F Jordan, M Szostak - ACS Catalysis, 2017 - ACS Publications
Functionalized biaryl-containing motifs are among the most valuable synthetic scaffolds in
organic chemistry with wide ranging commercial applications in pharmaceuticals, functional …

Transition metal-catalyzed organic reactions in undivided electrochemical cells

C Ma, P Fang, D Liu, KJ Jiao, PS Gao, H Qiu… - Chemical Science, 2021 - pubs.rsc.org
Transition metal-catalyzed organic electrochemistry is a rapidly growing research area
owing in part to the ability of metal catalysts to alter the selectivity of a given transformation …

Boryl Radical Activation of Benzylic C–OH Bond: Cross-Electrophile Coupling of Free Alcohols and CO2 via Photoredox Catalysis

WD Li, Y Wu, SJ Li, YQ Jiang, YL Li… - Journal of the …, 2022 - ACS Publications
A new strategy for the direct cleavage of the C (sp3)–OH bond has been developed via
activation of free alcohols with neutral diphenyl boryl radical generated from sodium …

Alcohols as Alkyl Synthons Enabled by Photoredox-Catalyzed Deoxygenative Activation

T Mandal, S Mallick, M Islam, S De Sarkar - ACS Catalysis, 2024 - ACS Publications
Alcohols are abundant with versatile structural variety and have ample use as pivotal
functional groups in numerous organic processes. Because of their frequent occurrence in …

Recent approaches for C–C bond formation via direct dehydrative coupling strategies

R Kumar, EV Van der Eycken - Chemical Society Reviews, 2013 - pubs.rsc.org
In recent years, reaction of inexpensive and abundantly available alcohols (C–OH) with
unactivated nucleophilic coupling partners (C–H), leading to the construction of the C–C …