A conformal TOF–DOI Prism‐PET prototype scanner for high‐resolution quantitative neuroimaging

X Zeng, Z Wang, W Tan, E Petersen, X Cao… - Medical …, 2023 - Wiley Online Library
Background Positron emission tomography (PET) has had a transformative impact on
oncological and neurological applications. However, still much of PET's potential remains …

A semi‐monolithic detector providing intrinsic DOI‐encoding and sub‐200 ps CRT TOF‐capabilities for clinical PET applications

F Mueller, S Naunheim, Y Kuhl, D Schug… - Medical …, 2022 - Wiley Online Library
Background Current clinical positron emission tomography (PET) systems utilize detectors
where the scintillator typically contains single elements of 3–6‐mm width and about 20‐mm …

Development of crosshair light sharing PET detector with TOF and DOI capabilities using fast LGSO scintillator

E Yoshida, F Obata, K Kamada… - Physics in Medicine …, 2021 - iopscience.iop.org
Objective. Time-of-flight (TOF) and depth-of-interaction (DOI) are well recognized as
important information to improve PET image quality. Since such information types are not …

Depth of interaction and coincidence time resolution characterization of ultrahigh resolution time-of-flight prism-PET modules

X Cao, A Labella, X Zeng, W Zhao… - IEEE Transactions on …, 2021 - ieeexplore.ieee.org
Depth-of-interaction (DOI) positron emission tomography (PET) detector with time-of-flight
(TOF) readout has been developed in recent years. With DOI, PET scanner could achieve …

High‐resolution and high‐sensitivity PET for quantitative molecular imaging of the monoaminergic nuclei: A GATE simulation study

Z Wang, X Cao, A LaBella, X Zeng, A Biegon… - Medical …, 2022 - Wiley Online Library
Purpose Quantitative in vivo molecular imaging of fine brain structures requires high‐spatial
resolution and high‐sensitivity. Positron emission tomography (PET) is an attractive …

Timing estimation of the exponentiated energy-weighted average for crosshair light sharing TOF-DOI PET detector

E Yoshida, F Obata, T Yamaya - … and Methods in Physics Research Section …, 2024 - Elsevier
In TOF-PET, the method of timestamp calculation is an important factor that affects
coincidence resolving time (CRT). In independent readout detectors, for one-to-one coupled …

Deep residual-convolutional neural networks for event positioning in a monolithic annular PET scanner

G Jaliparthi, PF Martone, AV Stolin… - Physics in Medicine & …, 2021 - iopscience.iop.org
PET scanners based on monolithic pieces of scintillator can potentially produce superior
performance characteristics (high spatial resolution and detection sensitivity, for example) …

A multi-resolution TOF-DOI detector for human brain dedicated PET scanner

W He, Y Zhao, W Huang, X Zhao, M Niu… - Physics in Medicine …, 2024 - iopscience.iop.org
Objective. We propose a single-ended readout, multi-resolution detector design that can
achieve high spatial, depth-of-interaction (DOI), and time-of-flight (TOF) resolutions, as well …

A CNN-based four-layer DOI encoding detector using LYSO and BGO scintillators for small animal PET imaging

W He, Y Zhao, X Zhao, W Huang, L Zhang… - Physics in Medicine …, 2023 - iopscience.iop.org
Objective. We propose a novel four-layer depth-of-interaction (DOI) encoding phoswich
detector using lutetium–yttrium oxyothosilicate (LYSO) and bismuth germanate (BGO) …

Resolving inter-crystal scatter in a light-sharing depth-encoding PET detector

E Petersen, A LaBella, Y Li, Z Wang… - Physics in Medicine & …, 2024 - iopscience.iop.org
Objective. Inter-crystal scattering (ICS) in light-sharing positron emission tomography (PET)
detectors leads to ambiguity in positioning the initial interaction, which significantly degrades …