[HTML][HTML] Synthetic biology tools for environmental protection

J Aminian-Dehkordi, S Rahimi, M Golzar-Ahmadi… - Biotechnology …, 2023 - Elsevier
Synthetic biology transforms the way we perceive biological systems. Emerging
technologies in this field affect many disciplines of science and engineering. Traditionally …

RB-TnSeq identifies genetic targets for improved tolerance of Pseudomonas putida towards compounds relevant to lignin conversion

AJ Borchert, A Bleem, GT Beckham - Metabolic Engineering, 2023 - Elsevier
Lignin-derived mixtures intended for bioconversion commonly contain high concentrations
of aromatic acids, aliphatic acids, and salts. The inherent toxicity of these chemicals places a …

Effects of broad-spectrum antibiotic (florfenicol) on resistance genes and bacterial community structure of water and sediments in an aquatic microcosm model

T Zhang, Y Ding, J Peng, Y Dai, S Luo, W Liu, Y Ma - Antibiotics, 2022 - mdpi.com
This study evaluates the effects of a broad-spectrum antibiotic (florfenicol) on antibiotic
resistance genes (ARGs) and bacterial community structure in aquatic environments. We …

Enhanced upgrading of lignocellulosic substrates by coculture of Saccharomyces cerevisiae and Acinetobacter baylyi ADP1

C Liu, B Choi, E Efimova, Y Nygård… - Biotechnology for Biofuels …, 2024 - Springer
Background Lignocellulosic biomass as feedstock has a huge potential for biochemical
production. Still, efficient utilization of hydrolysates derived from lignocellulose is challenged …

Natural transformation as a tool in Acinetobacter baylyi: streamlined engineering and mutational analysis

SR Bedore, EL Neidle, I Pardo, J Luo, AC Baugh… - Methods in …, 2023 - Elsevier
Natural transformation and homologous recombination in a soil bacterium, Acinetobacter
baylyi ADP1, occur with exceptionally high efficiency. These genetic features can be …

Evolution recovers the fitness of Acinetobacter baylyi strains with large deletions through mutations in deletion-specific targets and global post-transcriptional …

I Gifford, GA Suárez, JE Barrick - PLoS genetics, 2024 - journals.plos.org
Organelles and endosymbionts have naturally evolved dramatically reduced genome sizes
compared to their free-living ancestors. Synthetic biologists have purposefully engineered …

Natural transformation as a tool in Acinetobacter baylyi: Evolution by amplification of gene copy number

I Pardo, SR Bedore, MP Tumen-Velasquez… - Methods in …, 2023 - Elsevier
For many years, the natural competency of Acinetobacter baylyi ADP1 facilitated studies of
bacterial metabolism, biochemistry, and physiology. With the advent of synthetic biology …

[HTML][HTML] Metabolic engineering of Acinetobacter baylyi ADP1 for naringenin production

K Kurnia, E Efimova, V Santala, S Santala - Metabolic Engineering …, 2024 - Elsevier
Naringenin, a flavanone and a precursor for a variety of flavonoids, has potential
applications in the health and pharmaceutical sectors. The biological production of …

Carbon-wise utilization of lignin-related compounds by synergistically employing anaerobic and aerobic bacteria

E Meriläinen, E Efimova, V Santala… - Biotechnology for Biofuels …, 2024 - Springer
Background Lignin is a highly abundant but strongly underutilized natural resource that
could serve as a sustainable feedstock for producing chemicals by microbial cell factories …

A consortium-based approach to adaptive laboratory evolution of Acinetobacter baylyi ADP1 for lignin valorization

S Maiti, P Singh, A Muthukrishnan, LM Blank… - bioRxiv, 2024 - biorxiv.org
The utility of Acinetobacter baylyi ADP1 (ADP1) for lignin valorization has yet to be
sufficiently investigated compared to other organisms such as Pseudomonas, Rhodococcus …