[HTML][HTML] Leveraging big data of immune checkpoint blockade response identifies novel potential targets

Y Bareche, D Kelly, F Abbas-Aghababazadeh… - Annals of …, 2022 - Elsevier
Background The development of immune checkpoint blockade (ICB) has changed the way
we treat various cancers. While ICB produces durable survival benefits in a number of …

Comprehensive assessment of TECENTRIQ® and OPDIVO®: analyzing immunotherapy indications withdrawn in triple-negative breast cancer and hepatocellular …

G Roozitalab, B Abedi, S Imani, R Farghadani… - Cancer and Metastasis …, 2024 - Springer
Atezolizumab (TECENTRIQ®) and nivolumab (OPDIVO®) are both immunotherapeutic
indications targeting programmed cell death 1 ligand 1 (PD-L1) and programmed cell death …

Low expression of PGC-1β and other mitochondrial biogenesis modulators in melanoma is associated with growth arrest and the induction of an immunosuppressive …

KM Laurin, K Coutu-Beaudry, A Salazar, N Meribout… - Cancer Letters, 2022 - Elsevier
Mitochondria are specialized metabolic and immune organelles that have important roles in
tumor progression, metastasis, and response to chemotherapy and immunotherapy …