Abstract The AJCC Cancer Staging Manual, eighth edition published in late 2016, will
become the new global guideline for cancer diagnosis and treatment from January 1, 2018 …

More than 750 000 women in Italy are surviving a diagnosis of breast cancer. A large body
of literature tells us which characteristics impact the most on their prognosis. However, the …

Breast cancer treatment has advanced enormously in the last decade. Most of this is due to
advances reached in the knowledge regarding tumor biology, mainly in the field of diagnosis …

The host's immune system plays a crucial role in determining the clinical outcome of many
cancers, including breast cancer. Peripheral blood neutrophils and lymphocytes counts may …

Objective: To prospectively validate a previously discovered transcriptomic biomarker
consisting of 63 blood leukocyte gene expression (S63) values to discriminate between …

Objectives Many women with early-stage, hormone receptor-positive breast cancer may not
benefit from adjuvant chemotherapy. Gene expression tests can reduce chemotherapy over …

Background This study aimed to evaluate the prognostic significance of the Oncotype DX
recurrence score (RS) in T 1-2 N 1 M 0 estrogen receptor (ER)-positive, human epidermal …

Background Breast cancer is the most diagnosed malignancy in females in the United
States. The members of retinal determination gene network (RDGN) including DACH, EYA …

Adjuvant chemotherapy shows clear benefits in HER2-positive and triple-negative breast
cancer (BC). Its benefits are less universal in BCs expressing hormone receptors. The 21 …

Background: Breast cancer is the most common cancer in women across the world, with
high incidence and mortality rates. Being a heterogeneous disease, gene expression …