Proenkephalin as a biomarker correlates with acute kidney injury: a systematic review with meta-analysis and trial sequential analysis

LC Lin, MH Chuan, JH Liu, HW Liao, LL Ng… - Critical Care, 2023 - Springer
Abstract Background Proenkephalin A 119-159 (PENK) is freely filtered in the glomerulus
with plasma levels correlating with glomerular filtration rate. Therefore, PENK has been …

[PDF][PDF] Sensing dying cells in health and disease: the importance of kidney injury molecule-1

E Tutunea-Fatan, S Arumugarajah… - Journal of the …, 2024 - journals.lww.com
Abstract Kidney Injury Molecule-1 (KIM-1), also known as T cell immunoglobulin and mucin
domain-1 (TIM-1), is a widely recognized biomarker for acute kidney injury, but its biological …

Continuous and early prediction of future moderate and severe Acute Kidney Injury in critically ill patients: development and multi-centric, multi-national external …

F Alfieri, A Ancona, G Tripepi, A Rubeis, N Arjoldi… - PLoS …, 2023 - journals.plos.org
Background Acute Kidney Injury (AKI) is a major complication in patients admitted to
Intensive Care Units (ICU), causing both clinical and economic burden on the healthcare …

Machine-learning model for predicting oliguria in critically ill patients

Y Yamao, T Oami, J Yamabe, N Takahashi… - Scientific Reports, 2024 - nature.com
This retrospective cohort study aimed to develop and evaluate a machine-learning algorithm
for predicting oliguria, a sign of acute kidney injury (AKI). To this end, electronic health …

[HTML][HTML] Unveiling the enigma of acute kidney disease: predicting prognosis, exploring interventions, and embracing a multidisciplinary approach

SY Pan, TTM Huang, ZH Jiang, LC Lin… - Kidney Research and …, 2024 - ncbi.nlm.nih.gov
Acute kidney disease (AKD) is a critical transitional period between acute kidney injury and
chronic kidney disease. The incidence of AKD following acute kidney injury is approximately …

[HTML][HTML] Biomarkers in pursuit of precision medicine for acute kidney injury: hard to get rid of customs

KM Lin, CC Su, JY Chen, SY Pan… - Kidney Research and …, 2024 - ncbi.nlm.nih.gov
Traditional acute kidney injury (AKI) classifications, which are centered around semi-
anatomical lines, can no longer capture the complexity of AKI. By employing strategies to …

Bioinspired Multiantioxidant‐Cooperative Nanotheranostic Platform for Realizing Time‐Sensitive Management of Acute Kidney Injury

M Wu, L Lu, J Li, Q Guo, D Wang… - Advanced Functional …, 2023 - Wiley Online Library
Targeting the pivotal pathological processes of acute kidney injury (AKI) and parallelly
monitoring the treatment process has emerged as an intriguing strategy for the timely …

The furosemide stress test predicts the timing of continuous renal replacement therapy initiation in critically ill patients with acute kidney injury: a double-blind …

K Zhang, H Zhang, C Zhao, Z Hu, J Shang… - European Journal of …, 2023 - Springer
Background Continuous renal replacement therapy (CRRT) remains a crucial treatment for
critically ill patients with acute kidney injury (AKI), although the timing of its initiation is still a …

Urinary liver‐type fatty acid binding protein is a biomarker reflecting renal damage and the ameliorative effect of drugs at an early stage of histone‐induced acute …

K Ohata, T Sugaya, HN Nguyen, K Arai… - …, 2024 - Wiley Online Library
Aim Circulated histones play a crucial role in the pathogenesis of infectious diseases and
severe trauma, and it is one of the potential molecular targets for therapeutics. Recently, we …

Plasma neutrophil gelatinase-associated lipocalin independently predicts dialysis need and mortality in critical COVID-19

J Engström, H Koozi, I Didriksson, A Larsson… - Scientific Reports, 2024 - nature.com
Neutrophil gelatinase-associated lipocalin (NGAL) is a novel kidney injury and inflammation
biomarker. We investigated whether NGAL could be used to predict continuous renal …