Background Recently, the hallmarks of aging were updated to include dysbiosis, disabled
macroautophagy, and chronic inflammation. In particular, the low-grade chronic …

Human diseases have been a critical threat from the beginning of human history. Knowing
the origin, course of action and treatment of any disease state is essential. A microscopic …

Detection of extracellular vesicles (EVs) exosomes is a challenge to address the need for
better diagnostic tests and to create a point-of-care (POC) platform that can detect, monitor …

MicroRNAs (miRNAs) are a widely-studied class of non-coding RNAs characterized by their
short length (18-25 nucleotides). The precise functions of miRNAs are not well-elucidated; …

Extracellular vesicles (EVs) are vesicles with a lipid bilayer membrane on the outside, which
are widely found in various body fluids and contain biological macromolecules such as …

Breast cancer (BC) is the most common malignancy among women worldwide. Like many
other cancers, BC therapy is challenging and sometimes frustrating. In spite of the various …

Despite the advances in cancer treatment in recent years, the development of resistance to
cancer therapy remains the biggest hurdle towards curative cancer treatments. Therefore …

This review provides a comprehensive overview of our understanding of the role that
glycans play in the formation, loading and release of extracellular vesicles (EVs). The …

Endocrine homeostasis and metabolic diseases have been the subject of extensive
research in recent years. The development of new techniques and insights has led to a …

Long non-coding RNAs (lncRNAs) are a class of RNA transcripts more than 200 nucleotides
in length that play crucial roles in cancer development and progression. With the rapid …