The first microbial colonizers of the human gut: composition, activities, and health implications of the infant gut microbiota

C Milani, S Duranti, F Bottacini, E Casey… - Microbiology and …, 2017 - Am Soc Microbiol
The human gut microbiota is engaged in multiple interactions affecting host health during
the host's entire life span. Microbes colonize the neonatal gut immediately following birth …

The role of the microbiome in NAFLD and NASH

AA Kolodziejczyk, D Zheng, O Shibolet… - EMBO molecular …, 2019 - embopress.org
Nonalcoholic fatty liver disease (NAFLD) is the hepatic manifestation of cardiometabolic
syndrome, which often also includes obesity, diabetes, and dyslipidemia. It is rapidly …

mixOmics: An R package for 'omics feature selection and multiple data integration

F Rohart, B Gautier, A Singh… - PLoS computational …, 2017 - journals.plos.org
The advent of high throughput technologies has led to a wealth of publicly available 'omics
data coming from different sources, such as transcriptomics, proteomics, metabolomics …

From hairballs to hypotheses–biological insights from microbial networks

L Röttjers, K Faust - FEMS microbiology reviews, 2018 - academic.oup.com
Microbial networks are an increasingly popular tool to investigate microbial community
structure, as they integrate multiple types of information and may represent systems-level …

Antibiotic-induced microbiome depletion alters metabolic homeostasis by affecting gut signaling and colonic metabolism

A Zarrinpar, A Chaix, ZZ Xu, MW Chang… - Nature …, 2018 - nature.com
Antibiotic-induced microbiome depletion (AIMD) has been used frequently to study the role
of the gut microbiome in pathological conditions. However, unlike germ-free mice, the effects …

Maturation of the gut microbiome and risk of asthma in childhood

J Stokholm, MJ Blaser, J Thorsen… - Nature …, 2018 - nature.com
The composition of the human gut microbiome matures within the first years of life. It has
been hypothesized that microbial compositions in this period can cause immune …

Antibiotics as deep modulators of gut microbiota: between good and evil

G Ianiro, H Tilg, A Gasbarrini - Gut, 2016 - gut.bmj.com
The recent increase in our knowledge of human gut microbiota has changed our view on
antibiotics. Antibiotics are, indeed, no longer considered only beneficial, but also potentially …

[HTML][HTML] Factors influencing the gut microbiota, inflammation, and type 2 diabetes

L Wen, A Duffy - The Journal of nutrition, 2017 - Elsevier
The gut microbiota is a complex community of bacteria residing in the intestine. Animal
models have demonstrated that several factors contribute to and can significantly alter the …

Correlation and association analyses in microbiome study integrating multiomics in health and disease

Y Xia - Progress in molecular biology and translational …, 2020 - Elsevier
Correlation and association analyses are one of the most widely used statistical methods in
research fields, including microbiome and integrative multiomics studies. Correlation and …

Looking for a signal in the noise: revisiting obesity and the microbiome

MA Sze, PD Schloss - MBio, 2016 - Am Soc Microbiol
Two recent studies have reanalyzed previously published data and found that when data
sets were analyzed independently, there was limited support for the widely accepted …