Thiyl radicals in organic synthesis

F Denes, M Pichowicz, G Povie, P Renaud - Chemical reviews, 2014 - ACS Publications
Thiyl radicals have been used by nature in a broad range of biochemical processes. For
instance, thiol residues play an important role in many enzymatic processes as illustrated by …

Thiol-yne 'click'/coupling chemistry and recent applications in polymer and materials synthesis and modification

AB Lowe - Polymer, 2014 - Elsevier
This review highlights recent applications of the thiol-yne reaction in polymer synthesis and
modification and also gives some representative examples of its application in small …

Photoclick chemistry: a bright idea

BD Fairbanks, LJ Macdougall, S Mavila, J Sinha… - Chemical …, 2021 - ACS Publications
At its basic conceptualization, photoclick chemistry embodies a collection of click reactions
that are performed via the application of light. The emergence of this concept has had …

“Clicking” on/with polymers: a rapidly expanding field for the straightforward preparation of novel macromolecular architectures

K Kempe, A Krieg, CR Becer… - Chemical Society Reviews, 2012 - pubs.rsc.org
The combination of controlled polymerization techniques and “click” reactions form an
efficient platform for the preparation of polymers in various architectures. In this critical …

Bioorthogonal click chemistry: an indispensable tool to create multifaceted cell culture scaffolds

MA Azagarsamy, KS Anseth - 2013 - ACS Publications
Over the past decade, bioorthogonal click chemistry has led the field of biomaterial science
into a new era of diversity and complexity by its extremely selective, versatile, and …

Photo-induced radical thiol–ene chemistry: a versatile toolbox for peptide-based drug design

M Ahangarpour, I Kavianinia, PWR Harris… - Chemical Society …, 2021 - pubs.rsc.org
While the global market for peptide/protein-based therapeutics is witnessing significant
growth, the development of peptide drugs remains challenging due to their low oral …

Forging isopeptide bonds using thiol–ene chemistry: site-specific coupling of ubiquitin molecules for studying the activity of isopeptidases

EM Valkevich, RG Guenette, NA Sanchez… - Journal of the …, 2012 - ACS Publications
Chemical methods for modifying proteins can enable studies aimed at uncovering
biochemical function. Herein, we describe the use of thiol–ene coupling (TEC) chemistry to …

Externally stimulated click reactions for macromolecular syntheses

MA Tasdelen, B Kiskan, Y Yagci - Progress in Polymer Science, 2016 - Elsevier
Over the last decade, click chemistry reactions, that are fast, simple to use, easy to purify,
versatile, regiospecific, and give high product yields have gained significant importance for …

Thiol–yne coupling: revisiting old concepts as a breakthrough for up-to-date applications

A Massi, D Nanni - Organic & biomolecular chemistry, 2012 - pubs.rsc.org
Radical thiol–yne coupling (TYC) has emerged as one of the most appealing click chemistry
procedures, appearing as a sound candidate for replacing/complementing other popular …

Ethynyl-capped hyperbranched conjugated polytriazole: click polymerization, clickable modification, and aggregation-enhanced emission

J Wang, J Mei, E Zhao, Z Song, A Qin, JZ Sun… - …, 2012 - ACS Publications
Cu (I)-catalyzed azide–alkyne click polymerization, developed based on the click reaction,
has become a powerful tool for the construction of functional polytriazoles with linear and …