Recent developments in chromatographic purification of biopharmaceuticals
Over the last several decades, researchers have time and again proposed use of non-
chromatographic methods for processing of biotherapeutic products. However …
chromatographic methods for processing of biotherapeutic products. However …
The state of technological advancement to address challenges in the manufacture of rAAV gene therapies
Current processes for the production of recombinant adeno-associated virus (rAAV) are
inadequate to meet the surging demand for rAAV-based gene therapies. This article reviews …
inadequate to meet the surging demand for rAAV-based gene therapies. This article reviews …
Rapid affinity chromatographic isolation method for LDL in human plasma by immobilized chondroitin-6-sulfate and anti-apoB-100 antibody monolithic disks in …
T Liangsupree, E Multia, J Metso, M Jauhiainen… - Scientific reports, 2019 - nature.com
Low-density lipoprotein (LDL) is considered the major risk factor for the development of
atherosclerotic cardiovascular diseases (ASCVDs). A novel and rapid method for the …
atherosclerotic cardiovascular diseases (ASCVDs). A novel and rapid method for the …
Synthesis of reverse-selective nanoporous ultrafiltration membranes using dual phase separations of ionic liquid and Poly (ethylene glycol) from the gelating urea …
Many membranes with various pore structures have been studied for size-based selective
filtration and separation. However, one exhibiting reverse size selectivity has rarely been …
filtration and separation. However, one exhibiting reverse size selectivity has rarely been …
Molecularly imprinted macroporous polymer monolithic layers for L‐phenylalanine recognition in complex biological fluids
M Antipchik, A Dzhuzha, V Sirotov… - Journal of Applied …, 2021 - Wiley Online Library
In present work, the development of macroporous monolithic layers bearing the artificial
recognition sites toward L‐phenylalanine has been carried out. The set of macroporous poly …
recognition sites toward L‐phenylalanine has been carried out. The set of macroporous poly …
A novel porous silica monolith functionalized with 5-amino-1, 10-phenanthroline for SPE of metal ions in groundwater samples prior to their analysis using ICP-MS
AO AlSuhaimi, KM AlMohaimadi, BN AlAlawi, I Ali - Analytical Methods, 2018 - pubs.rsc.org
Porous silica monoliths are being used for favorable applications in separation science due
to their inherent characteristics such as their rigid skeleton, large surface area, affordable …
to their inherent characteristics such as their rigid skeleton, large surface area, affordable …
Selective immunoglobulin aggregates removal in antivenoms by a simple chromatographic step based on a monolithic stationary phase
NB Blanch, O Cascone, M Fingermann - Journal of Chromatography B, 2024 - Elsevier
Antivenom therapy is a critical intervention for treating the more than 5.000. 000
envenomation accidents that occur each year around the world. These immunotherapeutic …
envenomation accidents that occur each year around the world. These immunotherapeutic …
[HTML][HTML] Recent advances in antibody-based monolith chromatography for therapeutic applications
M González-González, K Mayolo-Deloisa… - Approaches to the …, 2020 - Elsevier
Monoliths are considered the fourth generation of chromatographic supports, and they
consist of a single piece of highly interconnected network of channels, distinguishing them …
consist of a single piece of highly interconnected network of channels, distinguishing them …
Method development for large molecules IEX separations
Liquid chromatography method development is defined by several key steps followed to end
up with a suitable analytical process. Generally, one determines the goal of the procedure …
up with a suitable analytical process. Generally, one determines the goal of the procedure …
[HTML][HTML] Assessment of thermally stabilized electrospun poly (vinyl alcohol) materials as cell permeable membranes for a novel blood salvage device
WJA Homer, M Lisnenko, AC Gardner… - Biomaterials …, 2023 - Elsevier
Abstract The use of Intraoperative Cell Salvage (ICS) is currently limited in oncological
surgeries, due to safety concerns associated with the ability of existing devices to …
surgeries, due to safety concerns associated with the ability of existing devices to …