Antimicrobial peptide production and plant-based expression systems for medical and agricultural biotechnology

E Holaskova, P Galuszka, I Frebort, MT Oz - Biotechnology advances, 2015 - Elsevier
Antimicrobial peptides (AMPs) are vital components of the innate immune system of nearly
all living organisms. They generally act in the first line of defense against various pathogenic …

Plant synthetic biology for producing potent phyto-antimicrobials to combat antimicrobial resistance

P Tiwari, T Khare, V Shriram, H Bae, V Kumar - Biotechnology Advances, 2021 - Elsevier
Inappropriate and injudicious use of antimicrobial drugs in human health, hygiene,
agriculture, animal husbandry and food industries has contributed significantly to rapid …

Functional peptides for plant disease control

E Montesinos - Annual Review of Phytopathology, 2023 - annualreviews.org
Plant disease control requires novel approaches to mitigate the spread of and losses
caused by current, emerging, and re-emerging diseases and to adapt plant protection to …

Discovery, optimization, and clinical application of natural antimicrobial peptides

AA Rodríguez, A Otero-González, M Ghattas… - Biomedicines, 2021 - mdpi.com
Antimicrobial peptides (AMPs) are widespread in multicellular organisms. These structurally
diverse molecules are produced as the first line of defense against pathogens such as …

Targeted gene delivery into various plastids mediated by clustered cell‐penetrating and chloroplast‐targeting peptides

C Thagun, JA Chuah, K Numata - Advanced Science, 2019 - Wiley Online Library
The plastid is an organelle that functions as a cell factory to supply food and oxygen to the
plant cell and is therefore a potential target for genetic engineering to acquire plants with …

Multiple roles of ribosomal antimicrobial peptides in tackling global antimicrobial resistance

HX Luong, HD Ngan… - Royal Society …, 2022 - royalsocietypublishing.org
In the last century, conventional antibiotics have played a significant role in global
healthcare. Antibiotics support the body in controlling bacterial infection and simultaneously …

Synthetic peptides against plant pathogenic bacteria

E Badosa, M Planas, L Feliu, L Montesinos… - Microorganisms, 2022 - mdpi.com
The control of plant diseases caused by bacteria that seriously compromise crop productivity
around the world is still one of the most important challenges in food security. Integrated …

Nicotiana benthamiana as a model plant host for Xylella fastidiosa: Control of infections by transient expression and endotherapy with a bifunctional peptide

A Baró, P Saldarelli, M Saponari… - Frontiers in plant …, 2022 - frontiersin.org
Transient expression of genes encoding peptides BP134 and BP178 by means of a Potato
virus X (PVX) based-vector system, and treatment with synthetic peptides by endotherapy …

A bifunctional synthetic peptide with antimicrobial and plant elicitation properties that protect tomato plants from bacterial and fungal infections

L Montesinos, B Gascón, L Ruz, E Badosa… - Frontiers in Plant …, 2021 - frontiersin.org
The hybrid peptide BP178 (KKLFKKILKYLAGPAGIGKFLHSAKKDEL-OH), derived from
BP100 (KKLFKKILKYL) and magainin (1–10), and engineered for plant expression, had a …

Antimicrobial Peptides With Antibiofilm Activity Against Xylella fastidiosa

L Moll, E Badosa, M Planas, L Feliu… - Frontiers in …, 2021 - frontiersin.org
Xylella fastidiosa is a plant pathogen that was recently introduced in Europe and is causing
havoc to its agriculture. This Gram-negative bacterium invades the host xylem, multiplies …