This review covers the literature published between January and December in 2018 for
marine natural products (MNPs), with 717 citations (706 for the period January to December …

Covering: up to 2020 The National Cancer Institute of the United States (NCI) has initiated a
Cancer Moonshot program entitled the NCI Program for Natural Product Discovery. As part …

Highlights•The small-molecule inhibitors targeting CD47/SIRPα axis, a promising
phagocytosis checkpoint in cancer therapy, are reviewed for the first time.•In addition to …

The varied pigments found in animals play both ecological and physiological roles. Virtually
all echinoderms contain putative pigment biosynthetic enzymes, the polyketide synthases …

Aurones and their synthetic analogues possess a wide-range of pharmacological activities,
which have been deciphered by various studies in the last decades. Aurones with potential …

Previously unreported anthraquinone, acetylpenipurdin A (4), biphenyl ether, neospinosic
acid (6), dibenzodioxepinone, and spinolactone (7) were isolated, together with (R)-6 …

The first representatives of the new fluorescent boro-β-carboline family were synthesized by
the insertion of the difluoroboranyl group into the oxaza or diaza core. The resulting …

Fluorescence is a widespread phenomenon found in animals, bacteria, fungi, and plants. In
marine environments fluorescence has been proposed to play a role in physiological and …

Two new water-soluble phenanthroperylene quinones, gymnochrome H (2) and
monosulfated gymnochrome A (3), as well as the known compounds gymnochrome A (4) …

Mitochondria are versatile organelles and function by communicating with cellular
ecosystems. The fluorescent colocalization analysis after fixation is a highly intuitive method …