Epstein–Barr virus latent genes

MS Kang, E Kieff - Experimental & molecular medicine, 2015 - nature.com
Abstract Latent Epstein–Barr virus (EBV) infection has a substantial role in causing many
human disorders. The persistence of these viral genomes in all malignant cells, yet with the …

The latent membrane protein 1 (LMP1)

A Kieser, KR Sterz - Epstein Barr Virus Volume 2: One Herpes Virus: Many …, 2015 - Springer
Almost exactly twenty years after the discovery of Epstein-Barr virus (EBV), the latent
membrane protein 1 (LMP1) entered the EBV stage, and soon thereafter, it was recognized …

Inhibition of NF-κB induces apoptosis of KSHV-infected primary effusion lymphoma cells

SA Keller, EJ Schattner… - Blood, The Journal of the …, 2000 - ashpublications.org
Kaposi sarcoma–associated herpesvirus (KSHV), or human herpervirus 8 (HHV-8), is a γ-
herpesvirus that infects human lymphocytes and is associated with primary effusion …

Epstein‐Barr virus infection and human malignancies

G Niedobitek, N Meru… - International journal of …, 2001 - Wiley Online Library
The Epstein‐Barr virus (EBV) is a herpes virus which establishes a life‐long persistent
infection in over 90% of the human adult population world‐wide. Based on its association …

LMP1 structure and signal transduction

AG Eliopoulos, LS Young - Seminars in cancer biology, 2001 - Elsevier
The oncogenic Epstein–Barr virus (EBV)-encoded latent membrane protein 1 (LMP1) has
structural features and functions reminiscent of a constitutively active TNF family receptor …

Role of NF-κB in cell survival and transcription of latent membrane protein 1-expressing or Epstein-Barr virus latency III-infected cells

ED Cahir-McFarland, K Carter, A Rosenwald… - Journal of …, 2004 - Am Soc Microbiol
Epstein-Barr virus (EBV) latency III infection converts B lymphocytes into lymphoblastoid cell
lines (LCLs) by expressing EBV nuclear and membrane proteins, EBNAs, and latent …

Epstein-Barr virus LMP1 activates EGFR, STAT3, and ERK through effects on PKCδ

CP Kung, DG Meckes Jr, N Raab-Traub - Journal of virology, 2011 - Am Soc Microbiol
Epstein-Barr virus (EBV) is a ubiquitous herpesvirus that infects more than 90% of the
world's adult population and is linked to multiple malignancies, including Burkitt lymphoma …

Epstein–Barr virus latent infection membrane protein 1 TRAF-binding site induces NIK/IKKα-dependent noncanonical NF-κB activation

M Luftig, T Yasui, V Soni, MS Kang… - Proceedings of the …, 2004 - National Acad Sciences
Epstein–Barr virus (EBV) latent infection membrane protein 1 (LMP1)-induced NF-κB
activation is important for infected cell survival. LMP1 activates NF-κB, in part, by engaging …

Latent membrane protein 1 is critical for efficient growth transformation of human B cells by Epstein-Barr virus

U Dirmeier, B Neuhierl, E Kilger, G Reisbach… - Cancer Research, 2003 - AACR
The EBV latent membrane protein 1 (LMP1) is an integral membrane protein that acts like a
constitutively activated receptor. LMP1 interacts with members of the tumor necrosis factor …

Oncogenic γ-herpesviruses: comparison of viral proteins involved in tumorigenesis

B Damania - Nature Reviews Microbiology, 2004 - nature.com
Herpesviruses are present in most species throughout the animal kingdom and are
classified into three subfamilies, α, β and γ, on the basis of their biological properties and …