Evaluation of pathological complete response as surrogate endpoint in neoadjuvant randomised clinical trials of early stage breast cancer: systematic review and …
Objective To evaluate pathological complete response as a surrogate endpoint for disease-
free survival and overall survival in regulatory neoadjuvant trials of early stage breast …
free survival and overall survival in regulatory neoadjuvant trials of early stage breast …
Functional nanomaterials for phototherapies of cancer
Cancer has been one of the major threats to the lives of human beings for centuries.(1)
Current cancer therapies mainly include surgery, chemotherapies, and radiotherapies …
Current cancer therapies mainly include surgery, chemotherapies, and radiotherapies …
Preoperative chemotherapy for operable colon cancer: mature results of an international randomized controlled trial
PURPOSE Neoadjuvant chemotherapy (NAC) has potential advantages over standard
postoperative chemotherapy for locally advanced colon cancer but requires formal …
postoperative chemotherapy for locally advanced colon cancer but requires formal …
Effect of duration of adjuvant chemotherapy for patients with stage III colon cancer (IDEA collaboration): final results from a prospective, pooled analysis of six …
T André, J Meyerhardt, T Iveson, A Sobrero… - The lancet …, 2020 - thelancet.com
Background A prospective, pooled analysis of six randomised phase 3 trials was done to
investigate disease-free survival regarding non-inferiority of 3 months versus 6 months of …
investigate disease-free survival regarding non-inferiority of 3 months versus 6 months of …
Duration of adjuvant chemotherapy for stage III colon cancer
A Grothey, AF Sobrero, AF Shields… - … England Journal of …, 2018 - Mass Medical Soc
Background Since 2004, a regimen of 6 months of treatment with oxaliplatin plus a
fluoropyrimidine has been standard adjuvant therapy in patients with stage III colon cancer …
fluoropyrimidine has been standard adjuvant therapy in patients with stage III colon cancer …
Radiomics features of multiparametric MRI as novel prognostic factors in advanced nasopharyngeal carcinoma
Purpose: To identify MRI-based radiomics as prognostic factors in patients with advanced
nasopharyngeal carcinoma (NPC). Experimental Design: One-hundred and eighteen …
nasopharyngeal carcinoma (NPC). Experimental Design: One-hundred and eighteen …
Metastasis-free survival is a strong surrogate of overall survival in localized prostate cancer
Purpose Adjuvant therapy for intermediate-risk and high-risk localized prostate cancer
decreases the number of deaths from this disease. Surrogates for overall survival (OS) could …
decreases the number of deaths from this disease. Surrogates for overall survival (OS) could …
Early relapse of follicular lymphoma after rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone defines patients at high risk for death: an analysis …
C Casulo, M Byrtek, KL Dawson, X Zhou… - Journal of Clinical …, 2015 - ascopubs.org
Purpose Twenty percent of patients with follicular lymphoma (FL) experience progression of
disease (POD) within 2 years of initial chemoimmunotherapy. We analyzed data from the …
disease (POD) within 2 years of initial chemoimmunotherapy. We analyzed data from the …
[HTML][HTML] A standardised, generic, validated approach to stratify the magnitude of clinical benefit that can be anticipated from anti-cancer therapies: the European …
The value of any new therapeutic strategy or treatment is determined by the magnitude of its
clinical benefit balanced against its cost. Evidence for clinical benefit from new treatment …
clinical benefit balanced against its cost. Evidence for clinical benefit from new treatment …
[HTML][HTML] Neoadjuvant immunotherapy for NSCLC: current concepts and future approaches
Lung cancer is the leading cause of cancer-related deaths worldwide. Patients with
resectable NSCLC are often treated with surgery and adjuvant chemotherapy. However …
resectable NSCLC are often treated with surgery and adjuvant chemotherapy. However …