The influence of comorbidities on COVID-19 outcomes has been recognized since the
earliest days of the pandemic. But establishing causality and determining underlying …

Background Cases of human monkeypox are rarely seen outside of west and central Africa.
There are few data regarding viral kinetics or the duration of viral shedding and no licensed …

Caring for critically ill patients is challenging in resource-limited settings, where the burden
of disease and mortality from potentially treatable illnesses is higher than in resource-rich …

We examined clinical outcomes of co-infection with influenza viruses, respiratory syncytial
virus, or adenoviruses in 212 466 adults with SARS-CoV-2 infection who were admitted to …

An outbreak of acute hepatitis of unknown aetiology in children was reported in Scotland in
April 2022 and has now been identified in 35 countries. Several recent studies have …

Objective To develop and validate a pragmatic risk score to predict mortality in patients
admitted to hospital with coronavirus disease 2019 (covid-19). Design Prospective …

Summary Background On Dec 31, 2019, China reported a cluster of cases of pneumonia in
people at Wuhan, Hubei Province. The responsible pathogen is a novel coronavirus, named …

Background Severe coronavirus disease 2019 (COVID-19) can manifest in rapid
decompensation and respiratory failure with elevated inflammatory markers, consistent with …

Structured abstract Objective To characterize the clinical features of patients with severe
COVID-19 in the UK. Design Prospective observational cohort study with rapid data …

The characterization of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
viral kinetics in hospitalized patients and its association with mortality is unknown. We …