Advances in soft mist inhalers

V Komalla, CYJ Wong, I Sibum… - Expert Opinion on …, 2023 - Taylor & Francis
ABSTRACT Introduction Soft mist inhalers (SMIs) are propellant-free inhalers that utilize
mechanical power to deliver single or multiple doses of inhalable drug aerosols in the form …

[HTML][HTML] Recent developments in lactose blend formulations for carrier-based dry powder inhalation

GA Hebbink, M Jaspers, HJW Peters… - Advanced Drug Delivery …, 2022 - Elsevier
Lactose is the most commonly used excipient in carrier-based dry powder inhalation (DPI)
formulations. Numerous inhalation therapies have been developed using lactose as a …

PLGA-based micro/nanoparticles: an overview of their applications in respiratory diseases

X Guo, X Zuo, Z Zhou, Y Gu, H Zheng, X Wang… - International Journal of …, 2023 - mdpi.com
Respiratory diseases, such as asthma and chronic obstructive pulmonary disease (COPD),
are critical areas of medical research, as millions of people are affected worldwide. In fact …

Particle engineering principles and technologies for pharmaceutical biologics

D Cun, C Zhang, H Bera, M Yang - Advanced Drug Delivery Reviews, 2021 - Elsevier
The global market of pharmaceutical biologics has expanded significantly during the last few
decades. Currently, pharmaceutical biologic products constitute an indispensable part of the …

Pulmonary drug delivery: an effective and convenient delivery route to combat COVID-19

S Alipour, L Mahmoudi, F Ahmadi - Drug delivery and translational …, 2023 - Springer
The recent outbreak of coronavirus disease 2019 (COVID-19) in Wuhan, China has spread
rapidly around the world, leading to a widespread and urgent effort to develop and use …

[HTML][HTML] The environmental impact of inhaled therapy: making informed treatment choices

A Woodcock, KM Beeh, H Sagara… - European …, 2022 - Eur Respiratory Soc
When selecting the best inhaler and drug combination for a patient with respiratory disease,
a number of factors should be considered. While efficacy and safety of medical treatments …

Drug combinations for inhalation: Current products and future development addressing disease control and patient compliance

H Banat, R Ambrus, I Csóka - International Journal of Pharmaceutics, 2023 - Elsevier
Pulmonary delivery is an alternative route of administration with numerous advantages over
conventional routes of administration. It provides low enzymatic exposure, fewer systemic …

[HTML][HTML] Novel applications of ultrasonic atomization in the manufacturing of fine chemicals, pharmaceuticals, and medical devices

H Naidu, O Kahraman, H Feng - Ultrasonics Sonochemistry, 2022 - Elsevier
Liquid atomization as a fluid disintegration method has been used in many industrial
applications such as spray drying, coating, incineration, preparation of emulsions, medical …

Nanostructures for drug delivery in respiratory diseases therapeutics: Revision of current trends and its comparative analysis

LÁ Ibarra-Sánchez, A Gámez-Méndez… - Journal of Drug Delivery …, 2022 - Elsevier
Respiratory diseases are leading causes of death and disability in developing and
developed countries. The burden of acute and chronic respiratory diseases has been rising …

In silico evaluation of particle transport and deposition in the airways of individual patients with chronic obstructive pulmonary disease

K Kadota, K Matsumoto, H Uchiyama, S Tobita… - European Journal of …, 2022 - Elsevier
Inhalation therapy can effectively treat chronic obstructive pulmonary disease (COPD), but
the physical factors determining the appropriate aerosol delivery into the targeted airways …