HLA-G: at the interface of maternal–fetal tolerance

LMR Ferreira, TB Meissner, T Tilburgs… - Trends in …, 2017 - cell.com
During pregnancy, semiallogeneic fetal extravillous trophoblasts (EVT) invade the uterine
mucosa without being rejected by the maternal immune system. Several mechanisms were …

A critical look at HLA-G

R Apps, L Gardner, A Moffett - Trends in immunology, 2008 - cell.com
Human leukocyte antigen-G (HLA-G) is a nonclassical HLA class-I molecule that was found
to be expressed by placental trophoblast cells 20 years ago. Because trophoblast forms the …

Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes

J Kowal, G Arras, M Colombo… - Proceedings of the …, 2016 - National Acad Sciences
Extracellular vesicles (EVs) have become the focus of rising interest because of their
numerous functions in physiology and pathology. Cells release heterogeneous vesicles of …

Surface expression of HLA-C antigen by human extravillous trophoblast

A King, TD Burrows, SE Hiby, JM Bowen, S Joseph… - Placenta, 2000 - Elsevier
In this paper definitive evidence that the classical class I product, HLA-C, is expressed on
the surface of normal trophoblast cells is provided. HLA-C transcripts were sequenced from …

[HTML][HTML] Monosomy of chromosome 3 and an inflammatory phenotype occur together in uveal melanoma

W Maat, LV Ly, ES Jordanova… - … & visual science, 2008 - tvst.arvojournals.org
purpose. In uveal melanoma, different predictors of poor prognosis have been identified,
including monosomy of chromosome 3, HLA expression, and the presence of infiltrating …

Characterization of monoclonal antibodies recognizing HLA-G or HLA-E: new tools to analyze the expression of nonclassical HLA class I molecules

C Menier, B Saez, V Horejsi, S Martinozzi… - Human immunology, 2003 - Elsevier
Nonclassical major histocompatibility complex (MHC) class I human leukocyte antigen E
(HLA-E) and HLA-G molecules differ from classical ones by specific patterns of transcription …

β2-microglobulin-free HLA class I heavy chain epitope mimicry by monoclonal antibody HC-10-specific peptide

F Perosa, G Luccarelli, M Prete, E Favoino… - The Journal of …, 2003 - journals.aai.org
Abstract mAb HC-10 loses its reactivity with HLA class I (HLA-I) H chain (HC) following its
association with β 2-microglobulin (β 2 m). Furthermore, the HC-10 defined epitope appears …

HLA class I allelic sequence and conformation regulate leukocyte Ig-like receptor binding

DC Jones, V Kosmoliaptsis, R Apps… - The Journal of …, 2011 - journals.aai.org
Abstract Leukocyte Ig-like receptors (LILRs) are a family of innate immune receptors
predominantly expressed by myeloid cells that can alter the Ag presentation properties of …

Direct selection of a human antibody fragment directed against the tumor T-cell epitope HLA-A1–MAGE-A1 from a nonimmunized phage-Fab library

P Chames, SE Hufton, PG Coulie… - Proceedings of the …, 2000 - National Acad Sciences
Antitumor antibodies with the same specificity as cytotoxic T lymphocytes that recognize
antigenic peptides encoded by tumor-associated genes and presented by MHC class I …

KIR3DL2 binds to HLA-B27 dimers and free H chains more strongly than other HLA class I and promotes the expansion of T cells in ankylosing spondylitis

I Wong-Baeza, A Ridley, J Shaw, H Hatano… - The Journal of …, 2013 - journals.aai.org
The human leukocyte Ag HLA-B27 (B27) is strongly associated with the spondyloarthritides.
B27 can be expressed at the cell surface of APC as both classical β 2-microglobulin …