Glaucoma is a progressive optic neuropathy in the eye, which is a leading cause of
irreversible blindness worldwide and currently affects over 70 million individuals. Clinically …

The last 30 years has seen a proliferation of research on protein-resistant biomaterials
targeted at designing bio-inert surfaces, which are prerequisite for optimal performance of …

AIM To report long-term outcomes of secondary glaucoma due to uveitis treated with Ahmed
glaucoma valve (AGV) implantation in a series of Chinese patients. METHODS The …

Silk fibroin is a versatile biomaterial with unique properties that is widely used in various
medical products, including surgical sutures and drug delivery systems. The development of …

Successful treatment of pathologies affecting eye depends on inherent activity of the drug, its
ability to cross several ocular barriers in order to reach biophase and most importantly its …

Excessive fibrosis following surgical procedures is a challenging condition with serious
consequences and no effective preventive or therapeutic option. Our group has previously …

Conventional drug administration mostly relies on systemic introduction of drugs into the
circulatory system. Before reaching the target site, the drugs must cross many biological …

Purpose Wound healing after Ahmed glaucoma valve (AGV) implantation often entails
fibrosis as a foreign body reaction to the silicone plate. Poly (2-methacryloyloxyethyl …

Significant endeavors can be made to develop effective drug delivery systems. Nowadays,
many of these novel systems have gained attention as they focus primarily on increasing the …

AIM To research the effect of Y-27632, a selective Rho-associated coiled-coil kinase
(ROCK) inhibitor, on TGF-β1/Smad2, 3 signal transduction in ocular Tenon's capsule …