Objective Precision medicine utilizes genomic and other data to optimize and personalize
treatment. Although more than 2,500 genetic tests are currently available, largely for extreme …

The diagnosis of GH deficiency (GHD) in childhood is a multistep process involving clinical
history, examination with detailed auxology, biochemical testing, and pituitary imaging, with …

Dopamine (DA) and norepinephrine (NE) are catecholamines primarily studied in the central
nervous system that also act in the pancreas as peripheral regulators of metabolism …

The importance of dopamine in central nervous system function is well known, but its effects
on glucose homeostasis and pancreatic β cell function are beginning to be unraveled …

Although long-studied in the central nervous system, there is increasing evidence that
dopamine (DA) has important roles in the periphery including in metabolic regulation. Insulin …

Dopamine is a key regulator of glucose metabolism in the central nervous system. However,
dopamine is also present in the periphery and may have direct effects on insulin-sensitive …

For decades, there have been observations demonstrating significant metabolic
disturbances in people with schizophrenia including clinically relevant weight gain …

Physical activity and exercise play critical roles in energy balance. While many interventions
targeted at increasing physical activity have demonstrated efficacy in promoting weight loss …

In the setting of rising rates of obesity and metabolic syndrome, characterized in part by
hyperinsulinemia, it is increasingly important to understand the mechanisms that contribute …

Purpose.: This study used dopamine D2 receptor (D2R) knockout (KO) mice to investigate
the role of D2R activity in the development of form-deprivation myopia (FDM). Sulpiride, a …