Exogenous ketone supplementation: an emerging tool for physiologists with potential as a metabolic therapy

K Falkenhain, H Islam, JP Little - Experimental physiology, 2023 - Wiley Online Library
Exogenous oral ketone supplements, primarily in form of ketone salts or esters, have
emerged as a useful research tool for manipulating metabolism with potential therapeutic …

Nutritional ketosis as a potential treatment for alcohol use disorder

VR Mahajan, SK Elvig, LF Vendruscolo… - Frontiers in …, 2021 - frontiersin.org
Alcohol use disorder (AUD) is a chronic, relapsing brain disorder, characterized by
compulsive alcohol seeking and disrupted brain function. In individuals with AUD …

Ketogenic diet: a potential adjunctive treatment for substance use disorders

D Kong, J Sun, J Yang, Y Li, K Bi, Z Zhang… - Frontiers in …, 2023 - frontiersin.org
Substance use disorders (SUD) can lead to serious health problems, and there is a great
interest in developing new treatment methods to alleviate the impact of substance abuse. In …

Ketogenic diet decreases alcohol intake in adult male mice

MC Blanco-Gandía, F Ródenas-González, M Pascual… - Nutrients, 2021 - mdpi.com
The classic ketogenic diet is a diet high in fat, low in carbohydrates, and well-adjusted
proteins. The reduction in glucose levels induces changes in the body's metabolism, since …

Ketogenic diet and behavior: insights from experimental studies

K Grabowska, M Grabowski, M Przybyła… - Frontiers in …, 2024 - frontiersin.org
As a journal page for full details. The ketogenic diet (KD) has been established as a
treatment for epilepsy, but more recently it has been explored as an alternative or add-on …

A complex interplay between nutrition and alcohol use disorder: Implications for breaking the vicious cycle

B White, S Sirohi - Current Pharmaceutical Design, 2024 - benthamdirect.com
Approximately 16.5% of the United States population met the diagnostic criteria for
substance use disorder (SUD) in 2021, including 29.5 million individuals with alcohol use …

Dose-dependent beneficial effect of ketone supplement-evoked ketosis on anxiety level in female WAG/Rij rats: Sometimes less is more

E Rauch, C Ari, Z Kovács - Nutrients, 2023 - mdpi.com
While one-third of the population can be affected by anxiety disorders during their lifetime,
our knowledge of the pathophysiology of these disorders is far from complete. Previously, it …

Dopaminergic and glutamatergic biomarkers disruption in addiction and regulation by exercise: A mini review

M Abdullah, LC Huang, SH Lin, YK Yang - Biomarkers, 2022 - Taylor & Francis
Introduction Drug addiction is associated with disruption of a multitude of biomarkers in
various brain regions, particularly in the reward centre. The most pronounced are …

Behavioral and biochemical effects of alcohol withdrawal in female C3H/HeNRj and C57BL/6JRj mice

S Tonetto, P Weikop, T Brudek… - Frontiers in Behavioral …, 2023 - frontiersin.org
Background Alcohol use disorder (AUD) is a major problem of our society and is often
characterized and worsened by relapse. Prolonged alcohol exposure leads to numerous …

Nutritional ketosis as treatment for alcohol withdrawal symptoms in female C57BL/6J mice

S Tonetto, P Weikop, M Thomsen - Scientific Reports, 2024 - nature.com
Upon both acute and prolonged alcohol intake, the brain undergoes a metabolic shift
associated with increased acetate metabolism and reduced glucose metabolism, which …