Synthetic lethality is a lethal phenomenon in which the occurrence of a single genetic event
is tolerable for cell survival, whereas the co-occurrence of multiple genetic events results in …

High‐throughput single‐cell RNA sequencing (scRNA‐seq) has advantages over traditional
RNA‐seq to explore spatiotemporal information on gene dynamic expressions in …

Inflammatory bowel disease (IBD) is a chronic immune-mediated condition arising due to
complex interactions between multiple genetic and environmental factors. Despite recent …

Background Xylem, the most abundant tissue on Earth, is responsible for lateral growth in
plants. Typical xylem has a radial system composed of ray parenchyma cells and an axial …

Wood formation is controlled by transcriptional regulatory networks (TRNs) involving
regulatory homeostasis determined by combinations of transcription factor (TF)–DNA and TF …

Wood formation is a complex process that involves cell differentiation, cell expansion,
secondary wall deposition, and programmed cell death. We constructed a four-layer wood …

Monolignol serves as the building blocks to constitute lignin, the second abundant polymer
on Earth. Despite two decades of diligent efforts, complete identification of all metabolites in …

Tension wood (TW) is a specialized xylem tissue developed under mechanical/tension
stress in angiosperm trees. TW development involves transregulation of secondary cell wall …

Lignin is one of the major components of xylem cell walls in tree stems. The lignin in the
wood of most flowering plants (dicotyledonous angiosperms) is typically polymerized from …

Hepatocellular carcinoma (HCC) is characterized by rapid growth, early vascular invasion,
and high metastasis. Currently available US Food and Drug Administration (FDA)‐approved …