Aptamer-based detection of circulating targets for precision medicine

L Wu, Y Wang, X Xu, Y Liu, B Lin, M Zhang… - Chemical …, 2021 - ACS Publications
The past decade has witnessed ongoing progress in precision medicine to improve human
health. As an emerging diagnostic technique, liquid biopsy can provide real-time …

Fundamentals and application of magnetic particles in cell isolation and enrichment: a review

BD Plouffe, SK Murthy, LH Lewis - Reports on Progress in …, 2014 - iopscience.iop.org
Magnetic sorting using magnetic beads has become a routine methodology for the
separation of key cell populations from biological suspensions. Due to the inherent ability of …

[HTML][HTML] Basic principles and recent advances in magnetic cell separation

M Frenea-Robin, J Marchalot - Magnetochemistry, 2022 - mdpi.com
Magnetic cell separation has become a key methodology for the isolation of target cell
populations from biological suspensions, covering a wide spectrum of applications from …

MXene-based cytosensor for the detection of HER2-positive cancer cells using CoFe2O4@ Ag magnetic nanohybrids conjugated to the HB5 aptamer

F Vajhadin, M Mazloum-Ardakani, M Shahidi… - Biosensors and …, 2022 - Elsevier
MXenes are a new class of conductive two-dimensional material which have received
growing attention in biosensing for their significant surface area and unique surface …

Nucleic acid aptamers in cancer research, diagnosis and therapy

H Ma, J Liu, MM Ali, MAI Mahmood… - Chemical Society …, 2015 - pubs.rsc.org
Aptamers are single-stranded DNA or RNA oligomers, identified from a random sequence
pool, with the ability to form unique and versatile tertiary structures that bind to cognate …

Aptamer-functionalized and gold nanoparticle array-decorated magnetic graphene nanosheets enable multiplexed and sensitive electrochemical detection of rare …

B Dou, L Xu, B Jiang, R Yuan, Y Xiang - Analytical chemistry, 2019 - ACS Publications
The identification and monitoring of circulating tumor cells (CTCs) in human blood plays a
pivotal role in the convenient diagnosis of different cancers. However, it remains a major …

Electrochemical detection of circulating tumor cells based on DNA generated electrochemical current and rolling circle amplification

C Shen, S Liu, X Li, M Yang - Analytical Chemistry, 2019 - ACS Publications
Circulating tumor cells (CTCs) are important indicators for tumor diagnosis and tumor
metastasis. However, the extremely low levels of CTCs in peripheral blood challenges the …

Ultrasensitive capture, detection, and release of circulating tumor cells using a nanochannel–ion channel hybrid coupled with electrochemical detection technique

J Cao, XP Zhao, MR Younis, ZQ Li, XH Xia… - Analytical …, 2017 - ACS Publications
With the growing demands of the early, accurate, and sensitive diagnosis for cancers, the
development of new diagnostic technologies becomes increasingly important. In this study …

DNA nanolithography enables a highly ordered recognition interface in a microfluidic chip for the efficient capture and release of circulating tumor cells

J Zhang, B Lin, L Wu, M Huang, X Li… - Angewandte …, 2020 - Wiley Online Library
Microfluidic chips with nano‐scale structures have shown great potential, but the fabrication
and cost issues restrict their application. Herein, we propose a conceptually new “DNA …

Micro total analysis systems: fundamental advances and biological applications

CT Culbertson, TG Mickleburgh… - Analytical …, 2014 - ACS Publications
It has been more than 20 years since the first micro total analysis systems (μTAS) papers
were published. Initial reports of these devices, which are also commonly referred to as …