Bile acids and their derivatives as potential modifiers of drug release and pharmacokinetic profiles

N Pavlović, S Goločorbin-Kon, M Ðanić… - Frontiers in …, 2018 - frontiersin.org
Bile acids have received considerable interest in the drug delivery research due to their
peculiar physicochemical properties and biocompatibility. The main advantage of bile acids …

[HTML][HTML] Lipid-core nanoparticles: Classification, preparation methods, routes of administration and recent advances in cancer treatment

P Graván, A Aguilera-Garrido, JA Marchal… - Advances in Colloid and …, 2023 - Elsevier
Nanotechnological drug delivery platforms represent a new paradigm for cancer
therapeutics as they improve the pharmacokinetic profile and distribution of …

Bile salts in digestion and transport of lipids

A Macierzanka, A Torcello-Gómez, C Jungnickel… - Advances in Colloid and …, 2019 - Elsevier
Because of their unusual chemical structure, bile salts (BS) play a fundamental role in
intestinal lipid digestion and transport. BS have a planar arrangement of hydrophobic and …

The role of bile salts in digestion

J Maldonado-Valderrama, P Wilde… - Advances in colloid and …, 2011 - Elsevier
Bile salts (BS) are bio-surfactants present in the gastrointestinal tract (GIT) that play a crucial
role in the digestion and absorption of nutrients. The importance of BS for controlled release …

[HTML][HTML] Food macromolecule based nanodelivery systems for enhancing the bioavailability of polyphenols

B Hu, X Liu, C Zhang, X Zeng - Journal of food and drug analysis, 2017 - Elsevier
Diet polyphenols—primarily categorized into flavonoids (eg, flavonols, flavones, flavan-3-
ols, anthocyanidins, flavanones, and isoflavones) and nonflavonoids (with major subclasses …

The influence of emulsion structure and stability on lipid digestion

M Golding, TJ Wooster - Current Opinion in Colloid & Interface Science, 2010 - Elsevier
The digestion and metabolism of lipids continues to generate considerable scientific interest,
with food emulsions increasingly being seen as a mechanism by which lipid uptake may be …

Review of in vitro digestion models for rapid screening of emulsion-based systems

DJ McClements, Y Li - Food & function, 2010 - pubs.rsc.org
There is increasing interest in understanding and controlling the digestion of emulsified
lipids within the food and pharmaceutical industries. Emulsion-based delivery systems are …

Colloidal aspects of digestion of Pickering emulsions: Experiments and theoretical models of lipid digestion kinetics

A Sarkar, S Zhang, M Holmes, R Ettelaie - Advances in Colloid and …, 2019 - Elsevier
Lipid digestion is a bio-interfacial process that is largely governed by the binding of the
lipase-colipase-biosurfactant (bile salts) complex onto the surface of emulsified lipid …

Modulating fat digestion through food structure design

Q Guo, A Ye, N Bellissimo, H Singh… - Progress in Lipid …, 2017 - Elsevier
Dietary fats and oils are an important component of our diet and a significant contributor to
total energy and intake of lipophilic nutrients and bioactives. We discuss their fate in a wide …

In vitro digestion of Pickering emulsions stabilized by soft whey protein microgel particles: influence of thermal treatment

A Sarkar, B Murray, M Holmes, R Ettelaie, A Abdalla… - Soft Matter, 2016 - pubs.rsc.org
Emulsions stabilized by soft whey protein microgel particles have gained research interest
due to their combined advantages of biocompatibility and a high degree of resistance to …