Chagas disease is a neglected tropical disease caused by the protozoan parasite
Trypanosoma cruzi. There is an urgent need for safe, effective, and accessible new …

Chagas disease, is a vector-mediated tropical disease whose causative agent is a parasitic
protozoan named Trypanosoma cruzi. It is a very severe health issue in South America and …

Cell-based screening has become the major compound interrogation strategy in Chagas
disease drug discovery. Several different cell lines have been deployed as host cells in …

Probing multiple proprietary pharmaceutical libraries in parallel via virtual screening allowed
rapid expansion of the structure–activity relationship (SAR) around hit compounds with …

We investigated the in vitro activity and selectivity, and in vivo efficacy of ravuconazole
(RAV) in self-nanoemulsifying delivery system (SNEDDS) against Trypanosoma cruzi. Novel …

Simple Summary Fusarium graminearum is a devastating plant pathogen that can cause
wheat head blight. Azole fungicides are commonly used chemicals for control of this …

Marine halophytes are an outstanding reservoir of natural products and several species
have anti-infectious traditional uses. However, reports about their potential use against …

Purpose The objective of this study was to molecularly characterize Mexican isolates of T.
cruzi obtained from infected triatomine bugs (the vectors of T. cruzi) and to evaluate their …

Chagas disease, or American trypanosomiasis, is a zoonosis caused by the hemoflagellate
parasite Trypanosoma cruzi. It is mainly transmitted by the bite of blood-sucking insects. It is …

Actualmente existen diferentes enfermedades desatendidas, entre esas se encuentra la
enfermedad de Chagas, que es una parasitosis sistémica causada por el protozoario …