Structural and chemical biology of terpenoid cyclases

DW Christianson - Chemical reviews, 2017 - ACS Publications
The year 2017 marks the twentieth anniversary of terpenoid cyclase structural biology: a trio
of terpenoid cyclase structures reported together in 1997 were the first to set the foundation …

Multiscale simulations of biological membranes: the challenge to understand biological phenomena in a living substance

G Enkavi, M Javanainen, W Kulig, T Róg… - Chemical …, 2019 - ACS Publications
Biological membranes are tricky to investigate. They are complex in terms of molecular
composition and structure, functional over a wide range of time scales, and characterized by …

Fern genomes elucidate land plant evolution and cyanobacterial symbioses

FW Li, P Brouwer, L Carretero-Paulet, S Cheng… - Nature plants, 2018 - nature.com
Ferns are the closest sister group to all seed plants, yet little is known about their genomes
other than that they are generally colossal. Here, we report on the genomes of Azolla …

[HTML][HTML] Microbial interactions: ecology in a molecular perspective

RM Braga, MN Dourado, WL Araújo - brazilian journal of microbiology, 2016 - SciELO Brasil
The microorganism-microorganism or microorganism-host interactions are the key strategy
to colonize and establish in a variety of different environments. These interactions involve all …

Ursolic acid and its derivatives as bioactive agents

S Mlala, AO Oyedeji, M Gondwe, OO Oyedeji - Molecules, 2019 - mdpi.com
Non-communicable diseases (NCDs) such as cancer, diabetes, and chronic respiratory and
cardiovascular diseases continue to be threatening and deadly to human kind. Resistance …

Low membrane fluidity triggers lipid phase separation and protein segregation in living bacteria

M Gohrbandt, A Lipski, JW Grimshaw… - The EMBO …, 2022 - embopress.org
All living organisms adapt their membrane lipid composition in response to changes in their
environment or diet. These conserved membrane‐adaptive processes have been studied …

Bacterial terpenome

JD Rudolf, TA Alsup, B Xu, Z Li - Natural product reports, 2021 - pubs.rsc.org
Covering: up to mid-2020 Terpenoids, also called isoprenoids, are the largest and most
structurally diverse family of natural products. Found in all domains of life, there are over 80 …

Bacterial membranes: structure, domains, and function

H Strahl, J Errington - Annual review of microbiology, 2017 - annualreviews.org
The bacterial cytoplasmic membrane is composed of roughly equal proportions of lipids and
proteins. The main lipid components are phospholipids, which vary in acyl chain length …

Hopanoid lipids: from membranes to plant–bacteria interactions

BJ Belin, N Busset, E Giraud, A Molinaro… - Nature Reviews …, 2018 - nature.com
Lipid research represents a frontier for microbiology, as showcased by hopanoid lipids.
Hopanoids, which resemble sterols and are found in the membranes of diverse bacteria …

Mini review: bacterial membrane composition and its modulation in response to stress

JR Willdigg, JD Helmann - Frontiers in Molecular Biosciences, 2021 - frontiersin.org
Antibiotics and other agents that perturb the synthesis or integrity of the bacterial cell
envelope trigger compensatory stress responses. Focusing on Bacillus subtilis as a model …